... 13, which until now has been treated with plasma exchange (PEX) and corticosteroids. A 29-year-old female patient, who presented with aTTP in the context of pregnancy, has developed multiple relapses after treatment with PEX, corticosteroids, and rituximab. Recently, caplacizumab, a nanobody against...

... prothrombin complex concentrates are ineffective for severe bleeding due to AFVD. Although several treatment strategies have been attempted, a standard of care for severe hemorrhage induced by AFVD is lacking. Herein, we report a case of AFVD with severe bleeding that responded to plasma exchange (PE...

...), initiated during the 15th week of her pregnancy, including corticosteroids, platelet aggregation inhibitors, hysterotomy, and splenectomy was ineffective. However, dramatic improvement and remission occurred after plasma exchange of 3,560 ml was performed with the Haemonetics Model 30 Blood Cell Separator...

...Mario Pini; Cesare Manotti; Alessandro Megha; Tullio Poli; Raffaele Poti 2 cases of acute idiopathic thrombotic thrombocytopenic purpura are reported. Both of them were treated with plasma exchange, antiplatelet drugs and prednisolone and both completely recovered. Plasma exchange appeared...

...Yoshitoshi Itoh; Tomoyuki Taniguchi; Naoshi Takeyama; Hideki Kuriki; Takaya Tanaka A 69-year-old woman with typical thrombotic thrombocytopenic purpura is reported, who was treated successfully by plasma exchange. An initial chromosomal analysis of peripheral blood lymphocytes revealed abnormal...

...Cavit Cehreli; Bahriye Payzin; Bulent Undar; Ugur Yilmaz; Mehmet N. Alakavuklar Two patients with paraneoplastic cerebellar degeneration accompanying Hodgkin’s disease were treated with plasma exchange in combination with chemotherapy or radiation therapy, respectively. Significant improvement...

... and ultimately complete remission of a resistant auto-immune haemolytic anaemia (AIHA) was achieved by carrying out preliminary plasma exchange as a crucial prelude to the administration of high-dose IV IgG provides not only insight into the immuno-regulatory action of the IgG but also raises the interesting...

...O. Kolker; S. Sviri; D.M. Linton; R. Or; A. Nagler; M.Y. Shapira Recognition of thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) following bone marrow transplantation (BMT) has increased in recent years. The use of plasma exchange has greatly improved the outlook of de novo...

...Javier de la Rubia; Aurelio López; Francisco Arriaga; Ana Rosa Cid; Ana Isabel Vicente; Maria Luisa Marty; Miguel A. Sanz We describe our experience in the management of 11 consecutive patients with thrombotic thrombocytopenic purpura (TTP) treated with a combined therapy of plasma exchange (PE...