... β°-thalassaemia (Sβ°-thal.)] has been the concern of all clinicians caring for these patients. Several agents have been tried for treatment, often limited by toxic side effects. Piracetam (2-oxo-1-pyrrolidine acetamide, Nootropyl®), a cyclic derivative of γ-amino butyrate, used for the treatment...

...R.C. Alvim; M.B. Viana; M.A.S. Pires; H.M.O.H. Franklin; M.J. Paula; A.C. Brito; T.F. Oliveira; P.V. Rezende Analgesia and hydration remain the only safe treatment for painful crises of sickle cell disease; hydroxyurea is effective, but the toxicity is still a problem. Piracetam is a nootropic drug...