... chromosomes Ph1 chromosome Acta Haemat. 48: 312-319 (1972) Heteromorphic Pair of Metacentric Chromosomes with Fused Arms and the Philadelphia Chromosome 1in a Case of Acute Myeloid Leukemia M. H. K han2 Zentrum der Inneren Medizin der Johann-Wolfgang-Goethe-Universität, Abteilung für Hämatologie (Direktor...

... a translocation of a second Ph1chromosome to a partially deleted short arm of one of the number 7 chromosomes (7p-) (fig. 3). In addition, there was elongation of the long arm of one of the number 9 chromosomes (9q+) and one Ph1 chromosome; that is, 45, XY,Ph>, t(9;22) (q34;ql2), dic(7;Ph ) (p 12;pl3). On January...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chromosome 19 CML Ph1 chromosome Translocation Acta haemat. 71: 124-127...

... interact with c-abl on other chromosomes than 22 [11], or operate independently [10-13], even without evi­ dence of the chimeric bcr-abl transcript [8]. Although the acquisition of the Ph1 chromosome may not be the seminal oncogenic event [14], it can be accepted that eradication of the Ph'-positive clone...

... Kyushu Cancer Center Notame 3-1-1 Minami-ku Fukuoka 815 (Japan) bcr-abl recombination bcr rearrangement Chronic myeloid leukemia In situ hybridization Ph1 chromosome Y chromosome © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... Polymerase chain reaction (PCR) Abstract A patient showing lymph node enlargement and tumors in the neck and axilla in the course of Philadelphia (Ph1) chromosome-positive chronic myeloid leu­ kemia (CML) was seen. There were no hematological findings suggestive of crisis. RNA was isolated from formalin...

...Pia Raanani; Luba Trakhtenbrot; Gideon Rechavi; Esther Rosenthal; Abraham Avigdor; Frida Brok-Simoni; Merav Leiba; Ninette Amariglio; Arnon Nagler; Isaac Ben-Bassat The Ph1 chromosome has rarely been reported in T-lineage acute lymphoblastic leukemia (T-ALL), and the clinical relevance...