...S.D. Douglas; G. Cohnen; E. König; G. Brittinger Peripheral blood lymphocytes from patients with chronic lymphocytic leukemia (CLL) had diminished and/or delayed in vitro responses to both phytohemagglutinin (PHA) and concanavalin A (Con A) as determined by thymidine incorporation into DNA, over...

...L.C. Giraudo Conesa; L. Rumi; M.E.M. Colmerauer; C. Dosne Pasqualini RNA extracted from normal liver of inbred rats was added to in vivo syngeneic peripheral leukocyte cultures enclosed within diffusion chambers, either 10 min after or 95 min before PHA. An increase in blastogenesis and DNA...

...G. Michlmayr; C. Huber; H. Braunsteiner; H. Huber Blood lymphocytes of normal individuals and of patients with chronic lymphocytic leukemia were evaluated for their blastogenic response to insoluble PHA. In at least preferential stimulation of normal B-lymphocytes was observed, whereas leukemic...

... myeloid leukaemia Cytotoxicity Leukaemic cell stimulation Mixed cell culture PHA Acta Haemat. 51: 129-139 (1974) Stimulation and Reactivity of Leukaemic Cells in Acute Myeloid Leukaemia G. D. P egrum, Carol A . E vans an d V alerie L. M iddleton Charing Cross Hospital Medical School, London...

... of 32, 35–36, 40–42, 45, 50, 54–55, 58–60, 70–75, and 90 were consistently observed. In PHA-stimulated lymphocytes, no discrete fraction slower than the 45S RNA was identified when the cells were incubated for periods longer than 15 min. However, the relative occurrence of molecules containing poly...

... of 40 days and the other 15 underwent random investigations during a period up to 10 months. Transient episodes of significant decreased lymphocyte transformation were revealed in 14 persons (58.4%) with regard to the spontaneous blastogenesis and in 11 subjects (45.8%) with regard to PHA-induced...