...Li Wang; Dong-Dong Wang; Rui-Ying Jiao; Chang-Xun Liu; Yan-Qiu Hou; Hui Qin; Hong-Jie He Objective: This study aimed to detect the association between P-selectin autoantibody positive and response to steroid treatment in newly diagnosed immune thrombocytopenia (ITP) patients. Methods: The data from...

... of platelet membrane glycoproteins GPIIb/IIIa (PAC-1) and P-selectin (CD62P) in rats. Results: The results showed that the GAG from U. unicinctus significantly inhibited the release of platelet calcium ( p < 0.01) and the expressions of platelet GPII b/IIIa and P-selectin ( p < 0.01) induced by ADP...

... to induce platelet activation (CD62p or P-selectin expression) in previous studies. We assessed the response of platelet count and CD62p expression after eradication therapy in patients with ITP and H. pylori infection. Methods and Results: We prospectively studied 15 ITP patients diagnosed with H. pylori...

... be severe thrombocytopenia these patients generally do not suffer from severe life-threatening hemorrhage. The plasma level of soluble P-selectin (sP-selectin) is a valuable marker reflecting platelet activation. Available data suggest that interleukin-6 (IL-6) may contribute to the regulation...