...; Hyeok Shim; Moo-Kon Song; Youngdoe Kim; Kihyun Kim Background: The neutrophil-to-lymphocyte ratio (NLR) is an independent prognostic marker in solid and hematological cancers. While the derived NLR (dNLR) was shown to be non-inferior to the NLR in large cohorts of patients with different cancer types...

...Zhongying Wang; Huahua Fan; Rufeng Xie; Jie Yang; Yana Ren; Yiming Yang; Wei Li Background/Aims: This study investigated the priming effect of sphingosine 1-phosphate (S1P) on formyl-Met-Leu-Phe-OH (fMLP)-activated neutrophils, by specific analysis of the neutrophil respiratory burst...

..., and IMPATH and Genzyme Genetics. Most of the granulocytes in the peripheral blood are neutrophil leukocytes, also known as PMN cells, a term that includes basophilic and eosinophilic leukocytes as well. Their nuclei are polymorphic on two accounts. First, they are segmented into two to five or more lobes...

...M.M. Speeckaert; C. Verhelst; A. Koch; R. Speeckaert; F. Lacquet Pelger-Huët anomaly (PHA), an autosomal dominant haematological trait is characterised by neutrophil nuclear hypolobulation and modified chromatin distribution. Mutations in the lamin B receptor gene, a member of the sterol reductase...

...Barbara J. Bain; S.N. Wickramasinghe A striking linear relationship was found between the logarithms of the medians of the circulating neutrophil (granulocyte plus metamyelocyte) counts and the monocyte counts in 5 groups of individuals studied. These groups consisted of (1) 100 normal adult males...

...C. Cassimos; S. Sklavunu-Zurukzoglu; D. Catriu; C. Nanas The ability of blood and bone marrow neutrophils to reduce nitroblue-tetrazolium both before and after stimulation with Escherichia cσli endotoxin was investigated. The polymorphonuclear cells of the bone marrow are less able to reduce...

...Ronald G. Strauss; Thomas G. Rosenberger; Peter D. Wallace Postphagocytic chemiluminescence of neutrophils was evaluated in infants throughout the 1st month of life, in their mothers and healthy adults to investigate further the defective chemiluminescence of neonatal neutrophils described...

...W. Sułowicz; H. Strzałka; M. Jakóbiec; W. Dawidiuk; M. Szczepaniec Neutrophil peroxidase activity was determined before delivery in 46 pregnant women. 36 of these women were also tested on the 1st day and 30 on the 3rd day after delivery. A significant increase in the average values of neutrophil...

...Ronald G. Strauss; Esther L. Snyder The concentration of total glutathione (GSH + GSSG) and its depletion during oxidant stress were studied in neutrophils obtained from human neonates, their mothers and adult controls to determine if the previously reported increased susceptibility of infant...

...Franco Dallegri; Franco Patrone; Guido Frumento; Loris Banchi; Carlo Sacchetti Normal human neutrophils, incubated with 0.2 mg/ml opsonized zymosan particles, were found to lyze human (H), ox (O) and chicken (C) red blood cell (RBC) targets as determined by the 51 Cr release assay...

...G. Carulli; A. Marini; A. Azzarà; M. Petrini; L. Ruocco; F. Ambrogi The effects of lithium on the microtubular and microfilament systems of neutrophil granulocytes is described. The phagocytic capacity of human neutrophils was reduced or inhibited by using vinblastine or cytochalasin B. Lithium...

...M. de Martino; M.E. Rossi; M. Resti; C. Vullo; A. Víerucci Superoxide anion production in resting and PMA- or zymosan-stimulated neutrophils was evaluated in 21 β -thalassemia patients. The results were correlated with ferritin values, hepatitis B virus serum markers, liver pathology...

... in neutrophilic granulocytes leaving all other cell types immuno-negative. 5 03 1991 3 04 1991 19 2 2009 © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...Sandra S. Kaplan; Roger L. Berkow; Robert A. Joyce; R.E. Basford; James C. Barton Functional analyses were performed on neutrophils isolated from 6 patients from two institutions who displayed features of chronic neutrophilic leukemia (CNL). These neutrophils demonstrated a consistent deficiency...

...E. Piva; S. De Toni; A. Caenazzo; M. Pradella; F. Pietrogrande; M. Plebani Neutrophil NADPH oxidase is a membrane-bound enzyme complex responsible for the reduction of oxygen to superoxide anion in the respiratory burst. Impaired neutrophil function has often been reported in myeloproliferative...

...Luci Maria Sant’Ana Dusse; Rívia Mara Morais e Silva; Vânia Maria Freitas; Geraldo Majella Medeiros de Paula; Lauro Mello Vieira; Maria das Graças Carvalho Pelger-Huët anomaly is an inherited condition characterized by hyposegmentation of the neutrophil nucleus and excessive chromatin clumping...

...N.A. Maianski; A.N. Maianski; T.W. Kuijpers; D. Roos Regulation of the neutrophil life span by apoptosis provides a fine balance between their function as effector cells of host defense and a safe turnover of these potentially harmful cells. Alterations of neutrophil apoptosis are associated...

...Satoshi Takagi; Kimiko Takahashi; Yoshiya Katsura; Takeshi Matsuoka; Akimichi Ohsaka Basic fibroblast growth factor (b-FGF) mediates a variety of biological responses such as angiogenesis and hematopoiesis. We examined the effect of b-FGF on human neutrophil functions in vitro. The surface...

... syndrome Granulocyte/colony-stimulating factor Neutrophils Since granulocyte/colony-stimulating factor (G-CSF) was introduced to enhance neutrophil counts, the number of documented infections has been reduced and cytotoxic chemotherapy has been performed more safely [ 1, 2 ]. Neutrophils...

...Akimichi Ohsaka; Katsu Saionji We examined the in vivo effect of granulocyte colony-stimulating factor (G-CSF) on the surface expression of putative counterligands for endothelial selectins on neutrophils in healthy volunteers. G-CSF (50 µg/m 2 /day) was administered subcutaneously to 5 healthy...