... correlated with the presence of recurrently mutated genes and if the markers were predictive for mutational status. Methods: Immunophenotypic data from 268 diagnostic AML samples obtained in 2009–2018 were analyzed retrospectively for the antigens CD34, CD117, CD123, and CLEC12A. Correlation between...

... identified 225 cases with α-thal and found that the prevalence of α-thal is 7.5% in this area. In molecular analyses, the α-thal gene mutations α 3.7 , α 4.2 , -- MED , -- 20.5 , α PA-2 α, ααα anti-3.7 , and α PA-1 α were detected. Conclusion: Our results showed that the α-thal mutations represent a great...

... of β-thalassemia mutations was attempted for 13 unrelated Japanese patients heterozygous for β-thalassemia. We have systematically analyzed β-thalassemia genes using polymerase-chain-reaction-related techniques; dot blot hybridization with oligonucleotide probes complementary to known mutations...

... understanding of the molecular pathology of mastocytosis. First, systemic mastocytosis has been found to be associated with activating codon 816 mutations of the c-kit gene. Second, this mutation was used as a tracking marker to elucidate the clonal nature of mastocytosis. These findings have resulted...