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1-20 of 179
Keywords: Multiple myeloma
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Journal Articles
Emicizumab and Acquired Hemophilia A Secondary to Multiple Myeloma
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2025)
Published Online: 24 April 2025
.... Case Presentation: We describe the successful management of AHA secondary to multiple myeloma (MM) using emicizumab and targeted anti-myeloma therapy. The patient initially responded to bortezomib-dexamethasone but required teclistamab due to disease progression. Emicizumab maintained hemostatic...
Journal Articles
Inflammatory Factors and Immune Cells in Relation to Multiple Myeloma
Available to PurchaseMeng-Jun Huang, Qing-Yi Zeng, Dan Chen, Chun-Xia Yang, Ying Yang, Man Zhou, Fen-Li Zhang, Qiu-Han Bian, Xiao-Yan Yang
Journal:
Acta Haematologica
Acta Haematol (2025)
Published Online: 11 February 2025
...Meng-Jun Huang; Qing-Yi Zeng; Dan Chen; Chun-Xia Yang; Ying Yang; Man Zhou; Fen-Li Zhang; Qiu-Han Bian; Xiao-Yan Yang Introduction: Many reports indicate that the occurrence of multiple myeloma (MM) is closely related to inflammation and immunity. Although the survival rates have been gradually...
Journal Articles
DRESS Is Not a Rare Complication during the Initial Treatment of Newly Diagnosed Multiple Myeloma: The Experience of Two Medical Institutes
Available to PurchaseJiao Yang, Qingqing Hu, Jiaqing Lu, Jian Wang, Die Wu, Xiaoming Fei, Lixia Wang, Xianqiu Yu, Yu Tang
Journal:
Acta Haematologica
Acta Haematol (2025)
Published Online: 27 January 2025
...Jiao Yang; Qingqing Hu; Jiaqing Lu; Jian Wang; Die Wu; Xiaoming Fei; Lixia Wang; Xianqiu Yu; Yu Tang Introduction: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity reaction rarely documented in patients with multiple myeloma (MM). Methods: In our...
Journal Articles
Historical Perspective of Allogeneic Hematopoietic Stem Cell Transplantation for Multiple Myeloma
Open AccessMuhammad Faisal Aslam, Asfand Yar Cheema, Daniyal Shahid, Bibi Maryam, Debduti Mukhopadhyay, Mishaal Munir, Ali Najam, Hossam M. Ali, Qaiser Bashir, Faiz Anwer
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (3): 315–329.
Published Online: 25 November 2024
...Muhammad Faisal Aslam; Asfand Yar Cheema; Daniyal Shahid; Bibi Maryam; Debduti Mukhopadhyay; Mishaal Munir; Ali Najam; Hossam M. Ali; Qaiser Bashir; Faiz Anwer Background: Advances in novel therapies have improved outcomes for multiple myeloma (MM) patients and the use of allo-SCT has decreased...
Journal Articles
Role of Autologous Transplant in Newly Diagnosed Multiple Myeloma Patients Treated with Novel Triplets: A Systematic Review and Meta-Analysis
Available to PurchaseIrina Amitai, Ronit Gurion, Pia Raanani, Iuliana Vaxman, Moshe Yeshurun, Hila Magen, Anat Gafter-Gvili, Liat Shargian
Journal:
Acta Haematologica
Acta Haematol 1–9.
Published Online: 16 September 2024
.... 2024 Multiple myeloma Autologous stem cell transplant Newly diagnosed myeloma Triplet Meta-analysis High-dose therapy with melphalan followed by stem cell rescue at the upfront setting (upfront autologous stem cell transplant [ASCT]) has been the standard of care for newly diagnosed...
Journal Articles
Real-World Risk of Severe Cytopenias in Multiple Myeloma Patients Sequentially Treated with Immunomodulatory Drugs
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (2): 135–147.
Published Online: 10 May 2024
...Julie Barberio; Timothy L. Lash; Ajay K. Nooka; Ashley I. Naimi; Rachel E. Patzer; Christopher Kim Introduction: Most multiple myeloma (MM) patients experience cytopenias, likely driven by both disease and treatment-related factors. Immunomodulatory agents (IMiDs), which form the backbone of most...
Journal Articles
Aimaz Afrough, Pearl Rajan Abraham, Laura Turer, Gurbakhash Kaur, Aishwarya Sannareddy, Doris K. Hansen, Larry D. Anderson Jr.
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (3): 300–314.
Published Online: 08 May 2024
... maturation antigen (BCMA), and both have recently gained approval by the US Food Drug Administration (FDA) for the treatment of relapsed and refractory multiple myeloma (RRMM). Summary: These therapies offer unprecedented responses in RRMM but present new challenges including cytokine release syndrome (CRS...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (3): 289–299.
Published Online: 06 May 2024
...Inbar Cohen; Iuliana Vaxman; Morie A. Gertz Background: High-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) has become part of standard of care (SOC) in newly diagnosed multiple myeloma. In this review, we provide a historical perspective on ASCT since its introduction...
Journal Articles
Xianghong Jin, Xianyong Jiang, Hui Li, Kaini Shen, Shuangjiao Liu, Miao Chen, Chen Yang, Bing Han, Junling Zhuang
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (1): 48–57.
Published Online: 16 April 2024
... remains controversial. This study aimed to investigate prognostic biomarkers for myeloma patients based on CPC presence. Methods: A comprehensive analysis was conducted on 309 consecutive patients diagnosed with either multiple myeloma or pPCL, utilizing peripheral blood smears stained with Wright-Giemsa...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2025) 148 (1): 36–47.
Published Online: 25 March 2024
...Jiaqi Shao; Enfan Zhang; Haoguang Chen; Zhen Cai; Mengmeng Dong Introduction: Multiple myeloma (MM) is a malignant proliferative disease of plasma cells. Abnormally cloned plasma cells secrete large amounts of monoclonal immunoglobulins in the bone marrow of MM patients. Serum urea nitrogen (sUN...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2024) 147 (6): 729–734.
Published Online: 06 March 2024
...Alexander D. Heini; Vera Ulrike Bacher; Dilara Akhoundova; Katja Seipel; Thomas Pabst Introduction: Bispecific antibodies have meaningfully expanded the therapeutic armamentarium in multiple myeloma. Talquetamab is a CD3+ T-cell-redirecting antibody targeting GPRC5D, which is expressed on multiple...
Journal Articles
Photon Counting Detector Computed Tomography: A New Frontier of Myeloma Bone Disease Evaluation
Open Access
Journal:
Acta Haematologica
Acta Haematol (2023) 146 (5): 419–423.
Published Online: 20 June 2023
... allows the generation of multi-energy images with increased contrast and scanning speed or ultra-high spatial resolution (UHR) images with lower radiation doses, compared to the currently used energy integrating detector (EID) CT. Since the recognition of bone disease related to multiple myeloma...
Journal Articles
Transient Daratumumab-Induced Refractive Shift in Multidrug-Resistant Multiple Myeloma: Case Report and Literature Review
Available to PurchaseSalvatore Troisi, Valentina Giudice, Mario Troisi, Denise Morini, Andrea Crudele, Bianca Cuffa, Carmine Selleri, Bianca Serio
Journal:
Acta Haematologica
Acta Haematol (2023) 146 (5): 424–430.
Published Online: 16 June 2023
...Salvatore Troisi; Valentina Giudice; Mario Troisi; Denise Morini; Andrea Crudele; Bianca Cuffa; Carmine Selleri; Bianca Serio Daratumumab, an anti-CD38 monoclonal antibody, is worldwide approved for treatment of newly diagnosed and relapsed/refractory multiple myeloma (MM) patients and is available...
Journal Articles
Once Monthly Elotuzumab and Lenalidomide Plus Dexamethasone for Multiple Myeloma: A Multicenter Observation Study
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2023) 146 (2): 125–136.
Published Online: 20 April 2023
...Kazuhito Suzuki; Morio Matsumoto; Yasushi Hiramatsu; Naoki Takezako; Yotaro Tamai; Kenshi Suzuki Introduction: Elotuzumab and lenalidomide plus dexamethasone (ERd) is a standard salvage chemotherapy for multiple myeloma, and elotuzumab is commonly administered every 2 weeks after cycle 3...
Journal Articles
Multicentric Castleman Disease and Concurrent Hematological Disorders: The Occurrence of Plasmacytoma and the Hypotheses Arising from Literature Review
Available to PurchaseAndrea Duminuco, Alessandra Romano, Elena Sabattini, Loredana Villari, Vittorio Del Fabro, Federica Elia, Giuseppe A. Palumbo, Francesco Di Raimondo, Concetta Conticello
Journal:
Acta Haematologica
Acta Haematol (2023) 146 (4): 334–340.
Published Online: 17 April 2023
...) and lymphoproliferative disorders, such as lymphomas. Instead, since the association with plasma cell diseases such as multiple myeloma and plasmacytoma is infrequent, there is a lack of literature. This manuscript aimed to revise the literature by describing a rare case of CD and plasmacytoma and attempting to explain...
Journal Articles
Prevalence and Clinical Characteristics of Paraproteinemia Associated with Chronic Myeloid Leukemia
Available to PurchaseTamar Berger, Adi Shacham Abulafia, Shai Shimony, Oren Pasvolsky, Iuliana Vaxman, Yifat Miron, Shimrit Feldman, Avi Leader, Pia Raanani
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (6): 619–626.
Published Online: 29 July 2022
... multiple myeloma (SMM, n = 2) and low-risk monoclonal gammopathy of undetermined significance (MGUS, n = 6). Six patients were on tyrosine kinase inhibitor treatment, 2 were in treatment-free remission. The only covariate associated with paraproteinemia was the presence of anemia, albeit with borderline...
Journal Articles
The Prognostic Impact of MYC Gene-Related Abnormalities on Multiple Myeloma Outcome through Fluorescence in situ Hybridization Analysis
Available to PurchaseYosuke Okada, Masahiro Teramoto, Noriaki Tachi, Toshikuni Kawamura, Toshikatsu Horiuchi, Shoichiro Kato, Takaaki Maekawa, Yukiko Osawa, Shinichi Kobayashi, Fumihiko Kimura
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (6): 582–591.
Published Online: 11 January 2022
... and prognostic value of multiple myeloma (MM). MYC gene-related abnormalities (MYC GAs) are one of the CAs, but their unfavorable impact has not been fully investigated in daily clinical practice. Methods: This study retrospectively analyzed the prognostic impact of MYC GAs on 81 patients through fluorescence...
Journal Articles
Increased Plasma GDF15 Is Associated with Altered Levels of Soluble VEGF Receptors 1 and 2 in Symptomatic Multiple Myeloma
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (3): 326–333.
Published Online: 24 November 2021
...Josefin Hidman; Anders Larsson; Måns Thulin; Torbjörn Karlsson Introduction: In multiple myeloma, there is an increase in bone marrow microvascular density and enhanced renal lymphangiogenesis. Increased levels of the proangiogenic protein growth differentiation factor-15 (GDF15) have previously...
Journal Articles
Survival Disparities in Multiple Myeloma by Health Insurance Status among US Non-Elderly Adults: A SEER-Based Comparative Analysis
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2021) 144 (5): 542–550.
Published Online: 30 March 2021
...Congyang Huang; Hanshan Liu; Li Jia; Min Lu; Suyun Hu Background/Aim: The impacts of health insurance status on survival outcomes in multiple myeloma (MM) have not been addressed in depth. The present study was conducted to identify definite relationships of cancer-specific survival (CSS...
Journal Articles
Burden of Treatment-Induced Peripheral Neuropathy in Patients with Multiple Myeloma in Sweden
Open AccessHareth Nahi, Göran Walinder, Vishal Patel, Ying Qu, Aaron Levine, Istvan Majer, Lucie Kutikova, Eva Hellqvist Franck, Maria K. Svensson, Markus Hansson
Journal:
Acta Haematologica
Acta Haematol (2021) 144 (5): 519–527.
Published Online: 25 February 2021
...Hareth Nahi; Göran Walinder; Vishal Patel; Ying Qu; Aaron Levine; Istvan Majer; Lucie Kutikova; Eva Hellqvist Franck; Maria K. Svensson; Markus Hansson Introduction: Treatment-induced peripheral neuropathy (TIPN) is a complication of multiple myeloma (MM) treatment. Objective: This real-world...
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