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Keywords: Mononine
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Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (1995) 94 (Suppl. 1): 53–58.
Published Online: 18 February 2009
... than PCCs and are less thrombogenic in vitro. In this report, the results of clinical studies with Mononine (Armour Pharmaceutical Company), a purified factor IX concentrate prepared by monoclonal affinity chromatography, are described. Two studies were performed, a phase I/II clinical trial in 10...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (1995) 94 (Suppl. 1): 25–34.
Published Online: 18 February 2009
... of this methodology, the steps included in the purification of the factor VIII concentrate Monoclate-P are reviewed and those used to purify the factor IX concentrate Mononine – monoclonal antibody chromatography, sodium thiocyanate incubation, and a novel ultrafiltration system – are described. Rigorous quality...