...Xue Yao; Hui Wang; Linhua Yang Introduction: Leukemia is a group of diseases caused by malignant hematopoietic stem cell clones. Leukemia ranks 13th in incidence and 10th in mortality, according to the Global Cancer Statistics 2022. Methods: We computed the prevalence, incidence, mortality...

...Deniz Seyithanoglu; Esra Nazligul Sert; Murat Ozbalak; Metban Mastanzade; Simge Erdem; Mustafa N. Yenerel Introduction: Changes in the number and functional capacity of T lymphocytes have been reported in chronic lymphocytic leukemia (CLL) patients. The aim of this study was to examine...

...Lili Pan; Yongzhi Zheng; Hao Zheng Introduction: Improved understanding of the prognostic biomarkers associated with childhood acute lymphoblastic leukemia (ALL) is needed for accurate risk group stratification. This study aimed to identify potential long non-coding RNA (lncRNA) markers...

... therapies for acute myeloid leukemia (AML) have not yet been described. Methods: Through retrospective review of 19,432 patients diagnosed with acute/chronic leukemia or myelodysplastic syndromes/myeloproliferative neoplasms (MDS+/−MPN) over 28 years, we calculated the incidence of SS in the setting...

...Xiaohui Cai; Jinfei Wang; Jingtao Lu; Zhuxia Jia; Meiyu Chen; Jianfang Liu; Xuzhang Lu; Hongying Chao Mixed lineage leukemia ( MLL) T10 is a relatively rare partner for the KMT2A lysine (K)-specific methyltransferase 2A gene. The common features and coexisting mutations of acute myeloid leukemia...

...Nadav Mizrahi; Eitan Kugler; Lucille Hayman; Moshe Yeshurun; Alon Grossman; Pia Raanani; Ofir Wolach The co-occurrence of thymoma and T-lymphoblastic lymphoma/leukemia is an extremely rare but previously reported association that poses a diagnostic and therapeutic challenge. We describe a 67-year...

... to in the content or advertisements. 2019 Table 3. Institution affiliated with more than 7 articles on the list Fig. 3. Number of articles originating from each country. Bibliometrics Citation classics Acute myelogenous leukemia Leukemia Neoplasms As medicine advances...

... chemotherapy and their relationship with markers of immunoparalysis in leukemia patients. In 6 patients with acute myeloid leukemia or myelodysplastic syndrome and 12 healthy subjects, DAMPs, cytokines, and markers of immunoparalysis were determined before and during the first week after chemotherapy...

... polymorphism is associated with risk of leukemia and to determine its prognostic effect. Material and Methods: Studies published in PubMed, Embase and the Cochrane Controlled Trial Register were searched till June 2014 using the search terms ‘MDM2', ‘polymorphism' and ‘leukemia'. Results: Eleven studies were...

... genes in human cancers. The demethylating, dose-dependent effect of arsenic trioxide (As 2 O 3 ) on several tumor-related genes has already been postulated. However, whether such a demethylating effect also applies to the TMS1 gene in chronic myeloid leukemia cell line K562 cells has not been studied so...

.... Our study cohort comprised 43 patients: 41 had allogeneic and 1 had autologous transplantation. One patient was waiting for transplantation. Patient age ranged from 43 to 79 years, 18 patients were male and 25 were female. Six patients suffered from acute lymphoblastic leukemia, 22 from acute myeloid...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemokines Gene expression Leukemia Multiple myeloma The chemokine CCL3/MIP-1α...

... the incidence of infection-related fever in 38 children, aged 2-16 years, with acute myeloid leukemia (AML) over 121 chemotherapy treatment cycles. A prophylactic group (n = 18) was given either vancomycin/cefepime (400 mg/m 2 , q12 h/50 mg/kg, q12 h) or piperacillin/tazobactam (110 mg/kg, q12 h). Control...

... with severe infections than without (8 vs. 39%; p ≤ 0.002). Patients who died by 12 weeks after GTX initiation were more likely to have leukemia (p = 0.03), not to have recovery of neutrophil counts (p < 0.0001), and to have started GTX during a critical care unit stay (p < 0.001). Uses of granulocyte...

... of leukemia. Methods: Ninety-three leukemia patients underwent allogeneic HSCT were divided into two groups: 51 cases of RD-HSCT and 42 cases of URD-HSCT. In the RD-HSCT group, a preconditioning regimen with fludarabine (Flu) + busulfan (Bu) + cytosine arabinoside (Ara-C) was used in 42 patients and total...

... Treatment of invasive fungal disease (IFD) remains difficult in severely immunosuppressed patients with leukemia or lymphoma [ 1 ] and in patients following allogeneic hematopoietic stem cell transplantation [ 2 ]. To improve treatment, researchers have explored the use of recombinant cytokines...

.... The data were obtained from systematic reviews and meta-analyses of randomized controlled trials (RCTs) published in this field, particularly in: (a) acute leukemia (as primary prevention of infections and as priming); (b) malignant lymphoma; (c) aplastic anemia; (d) autologous...

...Ron Ram; Anat Gafter-Gvili; Ofer Shpilberg; Pia Raanani In spite of decades of research in the field of allogeneic hematopoietic cell transplantation for the treatment of acute leukemia, controversies regarding the role of transplant still exist. These stem not only from contradictory results...

...Liyun Xiao; Yiqun Huang; Ruiji Zhen; J.W. Chiao; Delong Liu; Xudong Ma Objective: Since histone hypoacetylation due to excess histone deacetylases (HDACs) has been associated with transcriptional repression in leukemia, we aimed to determine deficient histone acetylation in patients with acute...

...H. Ohta; H. Nagase Serum muramidase values were greatly increased in all patients with monocytic leukemia, moderately elevated in chronic myelocytic leukemia, and only slightly increased in acute myelocytic leukemia. Serial estimations in patients with monocytic leukemia disclosed a sharp rise...