...Mirko Farina; Giuseppe Rossi; Daniella Bellotti; Eleonora Marchina; Robert Peter Gale A finding of cytogenetic abnormalities, even when these are clonal and even when the abnormalities are typically associated with leukaemia, is not the same as a person having leukaemia. We describe a person who...

... of solid tumours, but research on the correlation between PRAME and TRAIL gene expression in leukaemia patients is rare. Method: PRAME and TRAIL expression was detected in bone marrow samples from 80 newly diagnosed acute leukaemia (AL) patients and 40 chronic myeloid leukaemia (CML) patients using TaqMan...

...D. Ogston; Audrey A. Dawson; Helen M. Adam Components of the fibrinolytic enzyme system were measured in 22 adult patients with leukaemia, 21 with myelomatosis and 10 with myeloproliferative disorders. Alterations compatible with disseminated intravascular coagulation (DIC) were found in half...

...P.J. Toghill; D.R. Ryrie; M.K. Tanna; R.B. Tattersall 20 adults with acute myeloblastic, monomyeloblastic or monoblastic leukaemia have been treated with Rubidomycin. 6 Patients achieved complete remission and 2 partial remission. Smaller dosages of Rubidomycin were used than in previous series...

...G.L. Castoldi; G.D. Grusovin; G.L. Scapoli; R. Spanedda In a thalassaemic female carrying a 46, XX/46, XXqi mosaic, the occurrence of acute myeloblastic leukaemia was observed. Karyotype analysis of several bone marrow aspirates disclosed, besides both normal metaphases and metaphases containing...

...W. Queisser; A. Graubner; D. Hoelzer; U. Queisser; H. Heimpel In 7 cases of untreated and 2 cases of treated acute leukaemia (AL) the erythropoietic cell proliferation was studied by the combined method using AFeulgen-cytophotometry and autoradiography after labelling with 3H-TdR in vivo (1 h after...

... to in the content or advertisements. Cytochemistry Erythromyelosis Leukaemia Megakaryocytic myelosis Panmyelosis Acta Haemat. 50: 174-183 (1973) Unreifzeilige Panmyelose H. M eister und F. T rux Medizinische Klinik der Medizinischen Akademie Erfurt (Direktor: Prof. Dr.sc.med. Dr.h.c. Dr.h.c...

...M. Gahr; E. Jentsch; W. Schröter Haemoglobin fractions and 16 enzymatic activities of red cells of a patient with juvenile chronic myeloid leukaemia are compared to normal, to comparably reticulocyte-rich, non-neonatal and to fetal red cells. The activities of hexoki-nase, triosephosphate isomerase...

...M.D. Foadi In a girl with atypical acute leukaemia the malignant cell line in peripheral blood and bone marrow during three relapses was found to be tetraploid. The abnormal cells were more proliferative than those usually present in acute leukaemia. The tetraploid DNA content of the blast cells...

... period. GGT levels add no prognostic information to the routine haematological surveillance of leukaemia. Polychemotherapy does not appear to be an inducer of liver drug-metabolising microsomal enzymes. Polycythaemia rubra vera, myelofibrosis and chronic lymphocytic leukaemia may cause little change...

...U. Sjögren The mitotic indices of the eosinophilic precursors in the bone marrow of 3 untreated patients with eosinophilic leukaemia were found to be significantly lower than those of 11 patients with reactive eosinophilia and those of 15 healthy controls. The same differences were found...

...U. Sjögren The erythropoietic part of the bone marrow has been morphologically analysed in 34 untreated, anaemic patients with acute myeloid leukaemia and in 17 healthy controls. In the patients with leukaemia the percentage of basophilic erythroblasts was abnormally high and elevated mitotic...

...R. Billington; Ruth F. Itzhaki The resting lymphocytes of patients with chronic lymphocytic leukaemia (CLL) contain the same amount of RNA as do those of normal individuals, and in terms of different molecular species, as analyzed by polyacrylamide gels, there is very little to distinguish...

...Thomas J. Keane; Angela M. Gorman; Liam G. O’Connell; J.J. Fennelly In three cases of acute promyelocytic leukaemia remission was induced with cytosine arabinoside, daunarubicin and vincristine. The coagulopathy was controlled by EACA without resorting to the use of heparin. All three survived more...

...U. Sjögren Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients with chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase...

... clonal origin of leukaemia and the involvement of red cell precursors. © 1978 S. Karger AG, Basel 1978 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

...Ann Dickson; Barbara Birchmore 54 out of 112 patients with leukaemia have been shown to produce a lymphocytotoxin in their serum when the number of malignant cells present in the peripheral blood was considerably raised but the normal blood cells were low. This lymphocytotoxin reacts with all...

...U. Sjögren The mitotic indices of the granulopoietic precursor cells in the bone marrow of 3 untreated patients with acute eosinophilicmonocytic leukaemia were found to be significantly lower than those of 20 normals. The differences were found in the eosinophilic, the neutrophilic...

...Ann Dickson In 54 patients with leukaemia a raised incidence of HL-A9 was noted as well as a markedly increased association between this antigen and HL-A2. This occurred most frequently in patients with chronic myeloid leukaemia. As HL-A2 and HL-A9 are both antigens of the first series it has been...

...R.F. Hinchliffe; J.S. Lilleyman; N.F. Burrows; H.T. Swan Of 46 adult patients with active leukaemia whose white cells were examined using a Hemalog D automated differential leucocyte counter, 45 showed abnormalities indicative of their disease, and the odd one out would not have been missed due...