...G. De Rossi; D. Pasqualetti; G. De Sanctis; M. Lopez; M.L. Moleti; V. Bottari; C. Guglielmi; F. Mandelli An expansion of large granular lymphocytes (LGL) in the peripheral blood (PB) of a 10-year-old child is described. After a long history of uncertain hematological diagnosis and chemotherapeutic...

... of Medical Sciences, Jilin, P.R. China Characteristics of a Cell Line Established from a T Cell Acute Leukemia by Transfection with the bcl-2 Gene Key Words Acute leukemia bcl-2 Large granular lymphocytes T cell Transfection Abstract The bcl-2 gene product inhibits apoptosis and thus its over-expression may...

...Roberto Passetto Falcão; Belinda Pinto Simões; Aglair B. Garcia; Benedito A.F. Fonseca; João Terra Filho A 46-year-old woman with a previous diagnosis of sarcoidosis presented with morphologically typical large granular lymphocyte (LGL) leukemia/lymphoma with an aggressive clinical course. Epstein...

... with a primary form of PCL treated with VAD combination achieving an objective response, and who received high-dose melphalan and autologous peripheral blood stem cell (PBSC) transplantation followed by interferon-α. During the remission time, lasting for 3 years, an infiltration by large granular lymphocytes...

... A Large granular lymphocytes Pure red cell aplasia Large granular lymphocytes (LGL)/natural-killer-associated (NKa) disorders encompass a distinct clinical, morphological and immunological entity, the diagnostic criteria of which have been established previously [ 1, 2 ]. Patients...