... to the karyotype in 113 AML patients. Thus, FISH and molecular studies were found to add new information in 22 and 55% of the patients, respectively, particularly in cases with normal karyotype (NK) or when a cytogenetic analysis failed. Patients with NK changed their genetic risk group to favorable in 27 and 29...

... supposedly induced by busulphan therapy 6 years earlier. No clone formation or Ph 1 -chromosomes were found in the bone marrow. Haemorrhagic thrombocythaemia Karyotype Platelet life span © 1971 S. Karger AG, Basel 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... of chromosomal breakage. The findings in the distributions of breaks induced by alkylating agents and FUDR, however, show that the distribution studies related here are no practicable cytological criteria for the detection of different breakage mechanisms. Chromosome breakage Cytostatics Karyotype...

...G.L. Castoldi; G.D. Grusovin; G.L. Scapoli; R. Spanedda In a thalassaemic female carrying a 46, XX/46, XXqi mosaic, the occurrence of acute myeloblastic leukaemia was observed. Karyotype analysis of several bone marrow aspirates disclosed, besides both normal metaphases and metaphases containing...

... karyotypic findings. The karyotypicpattern of different cell lines was suggestive of a common stem cell origin. 5 3 2009 © 1972 S. Karger AG, Basel 1972 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...

...Phyllis Moores A normal 46, XX karyotype was demonstrated in an Indian woman who has 2 approximately equal populations of red cells and of leucocytes. She also has skin mosaicism. She is a normal female and has borne 4 healthy children. The ABO, Ss, Rh and Fy groups of her 2 red cell populations...

...J. Neuschatz; T.F. Necheles Severe factor IX deficiency (Christmas disease) in a phenotypically normal girl prompted a cytogenetic study of the proband and her parents which showed, in the patient, a karyotype with 46 chromosomes (XX ring) and a karyotype comprised of 45 chromosomes with a single X...

...Joel L. Moake; Harvey Lebos; Richard J. Warren All karyotypes of unstimulated blood leukocytes from a young adult patient with myelofibrosis myeloid metaplasia contained 2 small extra metacentric chromosomes which may have originated in a leukocyte stem cell line by long-arm breakage in chromosome...

..., instructions or products referred to in the content or advertisements. Chromosome anomalies Karyotype Myeloproliferative disorders Paroxysmal nocturnal haemoglobinuria Acta Haemat. 50: 350-356 (1973) Chromosome Studies in Paroxysmal Nocturnal Haemoglobinuria1 A lfonso Z accaria, P aolo R icci, M...

... a No. 13 chromosome. Both lymphocyte and skin fibroblast cultures revealed a normal female karyotype, which indicated that the abnormal karyotype was not constitutional but an aberration occurring only in the leukemic bone marrow cells. To our knowledge, such an aberration has not been reported previously...

...), University of Essen, Essen Abstract. The first case of a Ph'-negative chronic myelo­ Key Words cytic leukemia with a missing Y chromosome from bone Karyotype marrow cells is described. It is speculated that the benign Myelocytic leukemia course of the disease is due to the loss of the Y chromo­ Y chromosome...

... marrow chromosomes from the other patients showed a normal karyotype. 28 patients with IARSA, including our 6 patients, have had chromosomal analyses. Two consistent chromosomal abnormalities have been described: a + 8 in three patients and a 20q- in three others. Despite the presence of chromosomal...

... synthesis Karyotype Leukaemia Tetraploid blast cells Acta haemat. 57: 55-64 (1977) Tetraploid Cell Line in a Girl with Acute Leukaemia M. D. Foadi Department of Haematology, Institute of Child Health and The Hospital for Sick Children, London Key Words. Cell culture Cytokinetics DNA synthesis...

... Leukemia P reben E. P hilip Division of Hematology, Department of Medicine A, University Hospital of Copenhagen, Copenhagen Key Words. Chromosome aberrations Chromosome banding Karyotype Leukemic cells Myeloid leukemia Trisomy 11 Abstract. A female patient with chronic myeloid leukemia in acute...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic granulocytic leukaemia Karyotype Y chromosome Acta haemat. 54: 350-357 (1975) Absence of the Y Chromosome...

... bringing about the megaloblastoid changes may occur without influencing karyotype. © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chromosomal anomalies Karyotype Marker chromosome Myeloproliferative syndromes...

..., instructions or products referred to in the content or advertisements. Chronic myeloid leukemia Cytogenetics Karyotype Myeloproliferative disorders Philadelphia chromosome Y chromosome Acta haemat. 57: 310-320 (1977) Loss of the Y Chromosome from Bone Marrow Cells of Males with Myeloproliferative...

...J. Grozdea; G. Bourrouillou; C. Mounie; P. Colombies A comparative study of karyotypes, hematological variables and neutrophil alkaline phosphatase (NAP) was performed in 106 parents (53 couples) of children with free, homogeneous trisomy 21 and of 220 parents (110 couples) of normal children...

..., instructions or products referred to in the content or advertisements. B-cell immunoblastic non-Hodgkin’s lymphoma Karyotype Ph chromosome Acta haemat. 74: 171-174(1985) © 1985 S. Kargcr AG, Basel 0001-5792/85/0743-0171 $2.75/0 Ph Chromosome and B-Cell Malignancy-Associated Chromosomal Aberrations...