..., instructions or products referred to in the content or advertisements. Venous thrombosis Myeloproliferative neoplasms JAK2V617F Thrombophilia The BCR-ABL-negative myeloproliferative neoplasms (MPN) including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF...

... diagnosis and after IM follow-up. b Expression of the JAK2V617F mutant and BCR-ABL1 oncogene in 20 colonies collected at the time of CML diagnosis. HEL cells were used as a positive control (Ctrl+) for the homozygous JAK2V617F mutation. Expression of the housekeeping gene NCOA4 was used to verify...

... a case with concomitant ET and MM, where JAK2V617F was present in non-myeloma peripheral blood leukocytes and bone marrow (BM) hematopoietic cells, but not in BM-derived CD138-positive myeloma cells. In contrast, double-color fluorescence in situ hybridization analysis showed that BM-derived CD138...

... = 279 bp; normal allele = 229 bp. Fig. 1. JAK2V617F is present in the BM and PB of the 82-year-old male with lymphoma. aJAK2V617F was identified in the BM but not in either of the 2 gastric biopsies or the PB as of June 2006. Duplicate PCR reactions were performed by 2 operators in 3 runs. Identical...