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Keywords: JAK2 mutationClose
Aleksandra Leszczynska, Jolanta Grzenkowicz-Wydra, Lidia Chmielewska-Gorycka, Maria Bieniaszewska, Andrzej Hellmann
Acta Haematol (2016) 136 (2): 123–128.
Published Online: 14 July 2016
...Aleksandra Leszczynska; Jolanta Grzenkowicz-Wydra; Lidia Chmielewska-Gorycka; Maria Bieniaszewska; Andrzej Hellmann Introduction: The identification of mutations of the JAK2 gene is a useful marker in the diagnosis of polycythemia vera (PV) patients. We studied the frequency of JAK2 mutations...
Frauke Ringel, Jaspal Kaeda, Michaela Schwarz, Christian Oberender, Peggy Grille, Bernd Dörken, Fanny Marque, Paul W. Manley, Thomas Radimerski, Philipp le Coutre
Acta Haematol (2014) 132 (1): 75–86.
Published Online: 31 January 2014
... JAK2 mutation Tyrosine kinase inhibitors Chronic myeloproliferative neoplasms (CMPNs) are rare diseases of hematopoietic stem cells that are characterized by clonal expansion of one or more myeloid precursor cells. The four most frequent diseases of this group are chronic myelogenous leukemia...
C.M. Vadikolia, C. Tsatalas, K. Anagnostopoulos, G. Trypsianis, D. Pantelidou, I. Bazdiara, A. Anastasiadis, E. Spanoudakis, I. Kotsianidis, D. Margaritis, A. Kortsaris, G. Bourikas
Acta Haematol (2011) 126 (1): 54–62.
Published Online: 07 April 2011
... JAK2 V617F and may exhibit substantial overlap. Variability in JAK activation and allele burden, complemented by host, genetic and non-genetic modifiers, determine the phenotype. The aim of this study was to investigate the presence of the JAK2 mutation in association with the ratio...
Maria L. Randi, Fabiana Tezza, Margherita Scapin, Elena Duner, Pamela Scarparo, Raffaella Scandellari, Fabrizio Fabris
Acta Haematol (2010) 123 (3): 140–145.
Published Online: 04 February 2010
.... Essential thrombocythemia Polycythemia vera JAK2 mutation Unusual splanchnic or cerebral vein thrombosis Heparin-induced thrombocytopenia Over the last 10 years, we selected 29 patients with Ph-MPD (9 males and 20 females; 9 with polycythemia vera, PV, and 20 with essential thrombocythemia, ET...
Alessandro Allegra, Andrea Alonci, Giuseppa Penna, Arianna D’Angelo, Patricia Rizzotti, Angela Granata, Caterina Musolino
Acta Haematol (2009) 121 (4): 218–220.
Published Online: 29 May 2009
... in this unusual site in patients with ET, but the existence of a specific association between unexplained SVT and the JAK2 mutation has been reported. Methods and Results: The present study describes SVT (portal and splenic vein thrombosis) in a young woman as the first presenting symptom of latent ET. Extensive...