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1-20 of 52
Keywords: Iron overload
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Journal Articles
Bindanda Mvuama Van Timothee, Jing Du, Yuqiong Ren, Yuelin He, Yongsheng Ruan, Xuan Liu, Libai Chen, Jianyun Wen, Rongfang Ding, Li Yu, Qiujun Liu, Xiaoting Liu, Jianyun Liao, Zhiyong Peng, Xuedong Wu, Chunfu Li, Xiaoqin Feng
Journal:
Acta Haematologica
Acta Haematol 1–5.
Published Online: 25 August 2023
... overload on the mobilization of peripheral blood stem cells (PBSCs) in pediatric patients with β-thalassemia major (TM). Methods: We retrospectively reviewed the records of 226 patients with TM from whom PBSCs were collected. Iron overload was based on serum ferritin level, and liver and cardiac iron...
Journal Articles
Yaoyun Li, Yaqing Zhang, Lang Qin, Hangning Shang, Pingping Li, Bin Xiao, Yuhua Ye, Xiangmin Xu, Xinhua Zhang, Li Wang
Journal:
Acta Haematologica
Acta Haematol 1–7.
Published Online: 11 August 2023
... Splenectomy Iron overload Thalassemia is one of the most common monogenic genetic disorders worldwide, with a region-specific distribution that generally overlaps with areas experiencing the malaria endemic [ 1 ]. About 1–5% of the global population carries thalassemia mutations [ 2 ]. In China...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2021) 144 (3): 332–336.
Published Online: 02 October 2020
... months in grade 2; 33.2 ± 16.4%, median 144 ± 18 months in grade 1; p = 0.011); bone marrow iron overload ( p = 0.003; HR 1.7) and transfusion dependency (0.001; HR 2.6) negatively impacted on survival. We suggest that a higher grade of iron storage at diagnosis can impact on the outcome in MDS patients...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2019) 141 (4): 256–260.
Published Online: 09 April 2019
...Soumitra Tole; Ali Amid; Jillian Baker; Kevin Kuo; Jakob Pugi; Manuel Carcao Hereditary spherocytosis (HS) is a common inherited haemolytic anaemia and has great variability in its presentation. Non-transfusion iron overload in HS has only been reported with co-inheritance of hereditary...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2017) 138 (2): 119–128.
Published Online: 02 September 2017
...Yali Du; Zhangbiao Long; Miao Chen; Bing Han; Bo Hou; Feng Feng Background: This study focuses on the iron overload (IOL) of patients with transfused aplastic anemia (AA) or a low/intermediate-1 risk of myelodysplastic syndrome (MDS). Methods: Ninety-two AA or MDS patients with IOL were...
Journal Articles
Claire Sheeran, Donald K. Bowden, Sant-Rayn Pasricha, Ken Cheng, Giovanni Romanelli, Roger E. Peverill
Journal:
Acta Haematologica
Acta Haematol (2016) 135 (4): 200–207.
Published Online: 28 January 2016
...Claire Sheeran; Donald K. Bowden; Sant-Rayn Pasricha; Ken Cheng; Giovanni Romanelli; Roger E. Peverill Background/Aims: Hemoglobin H (HbH) disease is associated with iron overload, but whether this results in serious cardiac or vascular sequelae is unresolved. Methods: We identified 39 adult...
Journal Articles
Flávio Augusto Naoum, Breno Pannia Espósito, Lílian Piron Ruiz, Milton Artur Ruiz, Paula Yurie Tanaka, Juliana Tavora Sobreira, Rodolfo Delfini Cançado, José Carlos de Barros
Journal:
Acta Haematologica
Acta Haematol (2014) 131 (4): 222–226.
Published Online: 05 December 2013
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Labile plasma iron Hematopoietic stem cell transplantation Iron overload Toxicity Iron overload, whether transfusion-related or not, is a well-documented...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2013) 130 (2): 64–73.
Published Online: 26 August 2013
... and safety of oral iron chelators, and noninvasive techniques for the assessment of iron overload are translated into better patient outcomes. The construction of TM management guidelines facilitated the incorporation of such evidence into practice. However, as several aspects of the management of TM remain...
Journal Articles
Rodolfo Cancado, Maria Cristina A. Olivato, Paula Bruniera, Gilberto Szarf, Roberto de Moraes Bastos, Murilo Rezende Melo, Carlos Chiattone
Journal:
Acta Haematologica
Acta Haematol (2012) 128 (2): 113–118.
Published Online: 30 June 2012
...Rodolfo Cancado; Maria Cristina A. Olivato; Paula Bruniera; Gilberto Szarf; Roberto de Moraes Bastos; Murilo Rezende Melo; Carlos Chiattone The efficacy and safety of a 2-year treatment with deferasirox was evaluated in 31 patients with sickle cell anemia and transfusional iron overload. At 24...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2012) 128 (1): 28–32.
Published Online: 15 May 2012
... (exon 7, c.809A→T), a mutation previously reported only in 1 black patient with iron overload who resided in the Republic of South Africa. The present patient was also heterozygous for: heme transporter FLVCR1 novel allele P542S (exon 10, 1624C→T); FLVCR1 T544M (rs3207090); hemopexin (HPX) R371W...
Journal Articles
Paolo Ricchi, Silvia Costantini, Anna Spasiano, Tiziana Di Matola, Patrizia Cinque, Luciano Prossomariti
Journal:
Acta Haematologica
Acta Haematol (2011) 125 (4): 222–224.
Published Online: 27 January 2011
..., instructions or products referred to in the content or advertisements. Deferasirox Iron overload Pregnancy The therapeutic benefit of tailored iron chelation therapy and regular transfusions in patients with thalassemia major has significantly improved life expectancy; the number of women...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2011) 125 (4): 219–221.
Published Online: 25 January 2011
...A. Quarta; A. Melpignano; G. Quarta Iron overload sometimes complicates the clinical course of bone marrow transplantation and can cause damage to liver and heart function. A patient with post-transplantation secondary hemochromatosis was treated with deferasirox, which not only normalized ferritin...
Journal Articles
Nikolaos Chaliasos, Anna Challa, Eleftheria Hatzimichael, Freideriki Koutsouka, Dimitrios K. Bourantas, Antonios P. Vlahos, Antigone Siamopoulou, Konstantinos L. Bourantas, Alexandros Makis
Journal:
Acta Haematologica
Acta Haematol (2010) 124 (4): 191–196.
Published Online: 02 November 2010
...-thalassaemia, perhaps due to the toxic effect of iron overload on adipose tissue. Paradoxically, adiponectin levels are high and positively correlated with endothelin-1, raising questions about the pro- or anti-inflammatory role of this adipocytokine in beta-thalassaemia. 14 04 2010 3 08 2010 2...
Journal Articles
Ali Taher, Abdullah Al Jefri, Mohsen Saleh Elalfy, Kusai Al Zir, Shahina Daar, Diana Rofail, Jean François Baladi, Dany Habr, Ulrike Kriemler-Krahn, Amal El-Beshlawy
Journal:
Acta Haematologica
Acta Haematol (2010) 123 (4): 220–225.
Published Online: 27 April 2010
...Ali Taher; Abdullah Al Jefri; Mohsen Saleh Elalfy; Kusai Al Zir; Shahina Daar; Diana Rofail; Jean François Baladi; Dany Habr; Ulrike Kriemler-Krahn; Amal El-Beshlawy Patient-reported outcomes of once-daily oral deferasirox (Exjade®) in iron-overloaded patients with β-thalassemia not achieving...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2009) 122 (2-3): 134–139.
Published Online: 10 November 2009
... therapy although a randomized trial of phlebotomy versus no treatment has never been reported. Since the discovery of the HFE gene in 1996, it has been possible to predict the risk of developing iron overload by a simple blood test to detect C282Y homozygotes of the HFE gene. The application...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (1977) 57 (2): 96–101.
Published Online: 03 March 2009
...M. Westerhausen; G. Meuret A 71-year-old woman showed a highly unusual pattern of iron distribution in the organism which was associated with iron overload. The hallmark of this disease was an extreme hypersiderinemia, the serum iron reaching about 800 μ g/l00 ml. There was a pigment cirrhosis...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (1979) 61 (4): 209–215.
Published Online: 03 March 2009
... levels and unit of blood transfused on the other. The results of this study suggest that iron overload could be a cause of damage in the high frequency elements of the auditory mechanism. Intermittent hypoxia and slow 8th nerve compression due to bony hypertrophy as causes of auditory involvement...
Journal Articles
Chronic Liver Disease in Transfusion-Dependent Thalassemia: Liver Iron Quantitation and Distribution
S. De Virgiliis, G. Cornacchia, G. Sanna, F. Argiolu, R. Galanello, G. Fiorelli, M. Rais, P. Cossu, F. Bertolino, A. Cao
Journal:
Acta Haematologica
Acta Haematol (1981) 65 (1): 32–39.
Published Online: 27 February 2009
... active hepatitis, 23 with chronic persistent hepatitis, 22 with siderosis). Viral marker studies showed only 3 cases with both HBsAg and anti-HBc posiüvity in the serum, while the others had anti-HBc and anti-HBs or only anti-HBs or no B viral markers. A significantly higher iron overload was found...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (1980) 64 (5): 271–275.
Published Online: 27 February 2009
... was significantly higher than normal values indicating tissue excess and came down sharply after treatment with iron. In thalassaemia, associated presumably with iron overload, ascorbic acid status of platelets was definitely lower than normal indicating tissue deficiency. Leucocytic level of ascorbic acid...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (1983) 69 (1): 56–58.
Published Online: 26 February 2009
... to in the content or advertisements. Hemoglobin H Iron overload Radioimmunoassay Serum ferritin Short Communications Acta haemat. 69: 56-58(1983) © 1983 S. Karger AG, Basel 0001 -5792/83/0691 -0056 $ 2.75/0 Serum Ferritin Levels in Hemoglobin H Disease R. Galanello, M.A. Melis, E. Paglielli, G...
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