...Elena Santagostino; Guy Young; Carmen Escuriola Ettingshausen; Victor Jimenez-Yuste; Manuel Carcao The development of inhibitors against factor VIII (FVIII) concentrates represents a significant treatment complication for hemophilia. Immune tolerance induction (ITI) therapy eradicates inhibitors...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alkaline phosphatase Granulocytes Inhibitors Isoenzymes Leukemia Acta haemat. 73: 168-172(1985) © 1985S. Karger AG, Basel 0001-5792/85/0733-0168 $ 2.75/0 Changes...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Inhibitors Phorbol-myristate-acetate Platelet aggregation Acta Haemat 1988;80:210-215 © 198.x S. Karger AG. Basel 0001-5792/88/0804-0210 S 2.75 0 Phorbol-Myristate-Acetate-Induced...

...R.C.R. Ljung The nature of the mutation in the factor IX gene is an important factor in determining whether a patient with hemophilia B will develop an inhibitor. In a series of 62 Swedish families with hemophilia B, including 30 with the severe form, approximately one third of the families...

...Guy Young The most serious current complication of factor replacement therapy for hemophilia patients is the development of neutralizing antibodies to the factor termed inhibitors. Patients with high-titer inhibitors frequently develop serious bleeding complications which do not respond to standard...

...Kanjaksha Ghosh; Shrimati Shetty; Anil Pathare; Dipika Mohanty Haemophilia patients with inhibitors pose a formidable challenge for patient management. This is particularly problematic in developing countries, where porcine factor VIII, FEIBA, factor VIIa or immunoadsorption column are generally...

...Hale Ören; Işın Yaprak; Gülersu İrken In 58 hemophilia A patients aged 1–18 years (mean 9.5 ± 4.7 years), the prevalence of inhibitors was found to be 27% by the Bethesda method in November 1995. Inhibitor activity was not detected in any of 14 patients with mild hemophilia while it was present...