... type of the affected protein. Immunoglobulin light-chain (AL) amyloidosis is the most common form of systemic amyloidosis, characterized by deposition of a misfolded monoclonal light-chain that is secreted from a plasma cell clone. Demonstrating amyloid deposits in a tissue biopsy stained with Congo...

... monoclonal γ 3 heavy chain (HC) immunoglobulin molecule unattached to a light chain (LC) with atypical features for both MM and HC disease. Western blot showed γ 3 HC was truncated with a large deletion (75 kDa). Flow cytometry of the bone marrow aspirate revealed an unusual staining pattern. This plasma...

...B. Seitanidis; A. Mihas; B. Angelopoulos Serum immunoglobulin (IgG, IgA, IgM) levels have been determined in 22 splenectomized and 50 nonsplenectomized patients with β -thalassaemia major. Compared with 29 control subjects, all 3 immunoglobulins were statistically increased in the two thalassaemic...

.... Cryoglobulinemia Immunoglobulins Lymphoproliferative Macroglobulinemia Paraproteins Acta Haemat. 48: 183-190 (1972) Cryoglobulinemia Report of a Case with ;>M and yG Serum Gel F. Caronia, A. Patti, G. Donatuti and C. G uarnaccia Institute of Medical Pathology and Clinical Methodology (Director: Prof. G...

...J. Mirecka; G. Astaldi; Z. Szmigiel; J. Lisiewicz; M. Wazewska-Czyzewska The possibility of direct release of immunoglobulin from the erythrocyte surfaces due to the break of the erythrocyte-immunoglobulin binding after the i.v. administration of L-asparaginase has been shown in patients...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. EAC rosettes E rosettes Immunofluorescence Immunoglobulins Lymphoproliferative diseases Surface markers Acta...

...D.J.B. Perera; G.D. Pegrum An experimental system was designed to search for the presence of factors in the serum of patients with chronic lymphatic leukaemia (CLL) which might affect the viability of the lymphocytes. Washing was found to remove immunoglobulin from the surface of the lymphocytes...

... activity. These results suggest the presence of antibodies against new antigenic determinants which appear on immunoglobulin molecules following their reaction with the specific antigen. Further evidence for this hypothesis is supplied by the study of cryoprecipitates isolated from hyperimmune animal sera...

...N. Kaliakmanis; K. Melissinos; I. Economidou; K. Vlassopoulos Immunoglobulins IgG, IgM and IgA in the serum of 61 patients suffering from chronic renal failure of various etiology and not being under hemodialysis treatment were measured. Cases of nephropathy, due to collagen or blood disease...

.... Electrophoresis and separation of immunoglobulins suggest that the M-component is the pyroglobulin. In mixed cryoglobulinemias IgM- IgG, only the IgM is the pyroprecipitable component. The thermolability of pyroglobulins is due to a complex mechanism resulting from intramolecular or intermolecular reactions; itis...

...H. Asamer; R. Baumgartl; H. Braunsteiner In 3 patients with myeloma and paraprotein containing cells in the peripheral blood, we demonstrated by an immunofluorescent technique an increase in the number of lymphocytes and plasma cells with immunoglobulin determinants of paraprotein class specificity...

... in lymph node and spleen homogenates from this case. After splenectomy and cyclophosphamide the immunoglobulins decreased. It is suggested that both cases had a malignant lymphoma with plasmocytoid differentiation and polyclonal gammopathy. 3 3 2009 © 1976 S. Karger AG, Basel 1976 Copyright...

... 11%). In a separately performed combined assay for lymphocytes with membrane-bound immunoglobulins (M-Ig) and lymphocytes, which form rosettes with complement-coated bacteria (BC-RFC), four different fractions of lymphocytes could be detected: (M-Ig + -BC + , M-Ig +– BC – , M-Ig – -BC + , M-Ig – –BC...

... Deficiency F. Invernizzi, G. Balestrieri, G. Consogno, P. S. Riboldi and Angela Tincani Institute of Clinica Medica IV, University of Milan Key Words. Anti-IgA antibodies IgA deficiency Immunoglobulins Transfu­ sion reactions Abstract. A selective serum IgA deficiency with anti-IgA antibodies at high...

...A.S. Khalifa; J.M. Lusher; Jan Cejka; W.W. Zuelzer Levels of immunoglobulins G, A and M were determined in 55 children with idiopathic thrombocytopenic purpura (ITP) (32 acute, 18 chronic and 5 recurrent). Mean IgG levels tended to be low in acute ITP and returned to normal with recovery...

... hemolytic anemia was revealed, amounting to 7.2% of the patients. Of 68 patients who underwent serum immunoglobulin studies, up to 74% exhibited deficiency of at least one type of immunoglobulin. Low levels of IgA were encountered in 61.2%, IgM in 51.5% and IgG in 29.5% of the patients. 26 of 206 patients...

... DNA antigen Immunoglobulins Waldenströmߣs disease Acta haemat. 57: 344-350 (1977) Anti-y-Globulin Activity, DNA and Antibodies to DNA in Nonlupoid Cryoglobulinemias F. I nvernizzi, P. P ioltelli, G iovanna G avazzeni, P. S. R iboldi and C. Z anussi IV. Medical Clinic, University of Milan, Milan...

... Franklin’s disease γ-Heavy chain disease γ-Heavy chain disease proteins Immunoglobulins Immunoblastic sarcoma Malignant lymphoma Monoclonal gammopathy © 1978 S. Karger AG, Basel 1978 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cold agglutinins Immunoglobulins Lymphatic leukaemia Lymphocyte surface markers Acta haemat. 57: 206-210 (1977) Cold Agglutinins in a Case of Chronic Lymphatic...

.... Immunoglobulins Lymphomas (non-Hodgkin lymphomas) Multiple myeloma Short Communications Acta haemat. 63: 49-51 (1980) Non-Hodgkin Lymphoma Associated with Double Monoclonal Immunoglobulin Carlo Bartoloni, Giovanna Flamini, Nicola Gentiloni, Carlo Barone, Gino Gambassi and Tullio Terranova lstituti di...