...: MPV, glycocalicin and platelet-associated IgG (PA-IgG) were measured in 107 patients with idiopathic thrombocytopenic purpura (ITP) and 19 patients with hypoproductive thrombocytopenia (HPT; aplastic anemia or leukemia), and TPO was measured in 53 ITP and 12 HPT patients. All the included ITP patients...

...Domenico De Mattia; Giovanni Carlo Del Vecchio; Giovanna Russo; Attilio De Santis; Ugo Ramenghi; Lucia Notarangelo; Momcilo Jankovic; Angelo Claudio Molinari; Marco Zecca; Bruno Nobili; Paola Giordano Background/Objective: The management of chronic childhood idiopathic thrombocytopenic purpura (ITP...

...). Polymorphisms of the DNMT3B gene may influence DNMT3B activity on DNA methylation and increase the susceptibility to several diseases. The current study investigated the association between DNMT3B 579G>T and the risk for idiopathic thrombocytopenic purpura (ITP). The DNMT3B 579G>T polymorphisms were...

...W.A. Veenhoven; J.A. Kaars Sijpesteijn; G.S. van der Schans A group of 40 patients with idiopathic thrombocytopenic purpura (ITP) was examined. Typing for HLA A and B antigens was performed. The frequencies of 24 HLA antigens in this group were compared with those of a group of 13 patients...

... thrombocytopenic purpura and in 11 patients with thrombocytopenia associated with chronic liver disease. Bone marrow smears were also examined and megakaryocytes classified into stages I–III according to the current principle. Of 12 patients with idiopathic thrombocytopenic purpura the percentage...

...Yoshiyuki Kurata; Tadahiro Tsubakio; Takeshi Yonezawa; Seiichiro Tarui High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase...

...W. Spruce; S. Forman; R. McMillan; M. Farbstein; M. Turner; K. Blume A 25-year-old female developed idiopathic thrombocytopenic purpura 1 year after undergoing bone marrow transplantation for acute myelogenous leukemia. She had a complete response after splenectomy. The patient’s posttransplant...

...Kai Gjerløff Schmidt; Jens Wæver Rasmussen; Inger Marie Wedebye; Erik Øster-Jørgensen In 2 cases of idiopathic thrombocytopenic purpura a transient increase in platelet count was observed during and following infectious episodes. This association which is in contrast to the previously reported...

...Giuseppe G. Nenci; Giancarlo Agnelli; Maria De Cunto; Paolo Gresele Three infusions of vincristine-loaded platelets were carried out in a young man with acute idiopathic thrombocytopenic purpura (ITP) refractory to steroids. This procedure, used until now only for chronic refractory ITP, insured...

...G.M. Gandolfo; A. Afeltra; M.A. De Ruggieri; M.A. Ernandez The concentrations of serum immunoglobulins were determined in 44 adults with idiopathic thrombocytopenic purpura. A significant reduction of the mean IgA level was observed, while no differences were demonstrated as concerns IgG and IgM...

...) and to accelerated destruction in 28 cases (27 idiopathic thrombocytopenic purpura). Six volume variables were retained from the platelet volume distribution curves. A multivariate discriminant analysis has shown that the median of the curves was the most discriminant parameter between the two types...

...Giuseppe Leone; Luigi Maria Larocca; Donata Scribano; Sergio Storti; Giovanni Caputo; Raffaele Landolfi The modifications of cell-mediated immunity in idiopathic thrombocytopenic purpura (ITP) were investigated using the technique of Moretta et al. [J. exp. Med. 151: 969–974, 1980] to study T...

...Shinobu Nakamura; Takashi Yoshida; Shigeki Ohtake; Tamotsu Matsuda Two adult patients with chronic idiopathic thrombocytopenic purpura (ITP) were treated with high-dose intact immunoglobulin (high-dose IgG). Haptoglobin levels in both cases declined significantly during high-dose IgG, following...

...Mohammed S. El-Khateeb; Abdulla S. Awidi; Musleh S. Tarawneh; Mahmoud Abu-Khalaf Thirty-three patients with idiopathic thrombocytopenic purpura (ITP) were tested for HLA-A, B and C antigens, platelet antibodies, immunoglobulin levels and ABO blood groups. With one exception, ITP proved...

...Tadahiro Tsubakio; Yoshiyuki Kurata; Yoshio Kanayama; Takeshi Yonezawa; Seiichiro Tarui; Teruo Kitani In vitro phagocytosis of platelets from patients with idiopathic thrombocytopenic purpura (ITP) (direct assay) and phagocytosis of normal platelets sensitized with patient serum (indirect assay...

...M. Buelli; S. Cortelazzo; P. Viero; B. Minetti; B. Comotti; R. Bassan; T. Barbui Fourteen patients with idiopathic thrombocytopenic purpura (ITP) refractory to steroids and/or splenectomy were treated with danazol (200 mg 3 times a day) for 2 months. The following responses were achieved: excellent...

...M. Linares; A. Cervero; M. Sanchez; S. Garcia; A. Miguel-Sosa; A. Miguel-Garcia; J.M. Miguel-Borja Eight patients with idiopathic thrombocytopenic purpura (ITP), who were refractory to glucocorticoid therapy, were given slow infusions of vincristine (VCR) over a 4- to 6-hour period at weekly...

...Shosaku Nomura; Mutsumasa Yanabu; Tetsuji Soga; Hirofumi Kido; Tsutomu Fukuroi; Kazuyuki Yamaguchi We analyzed the immunological characteristics of patients with idiopathic thrombocytopenic purpura (ITP) and antiglycoprotein (GP) IIb/IIIa or GPIb autoantibodies. Among 101 ITP patients, 32 had anti...

...T. Furubayashi; H. Mizutani; H. Take; S. Honda; Y. Tomiyama; S. Katagiri; T. Tamaki; T. Tsubakio; Y. Kurata; T. Yonezawa; S. Tarui Autologous mixed lymphocyte reaction (AMLR)-induced suppressor function was studied in 12 patients with chronic idiopathic thrombocytopenic purpura (ITP). The function...

... 12 05 1993 18 2 2009 Case Report Acta Haematol 1993;89:209-212 Haruki Kondo Shinya Sakai Yuzo Sakai Division of Hematology, Department of Medicine, Shimizu Kousci Hospital, Shimizu, Shizuoka, Japan Autoimmune Haemolytic Anaemia, Sjogren's Syndrome and Idiopathic Thrombocytopenic Purpura...