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Keywords: Hypochromia
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Journal Articles

Haemoglobin E Variants: a Clinical, Haematological and Biosynthetic Study of 4 South African Families

Subject Area:
Hematology , Oncology
A.R. Bird, K. Wood, F. Leisegang, C.G. Mathew, P. Ellis, P.S. Hartley, C.D. Karabus
Journal: Acta Haematologica
Acta Haematol (1984) 72 (2): 135–137.
https://doi.org/10.1159/000206374
Published Online: 25 February 2009
...A.R. Bird; K. Wood; F. Leisegang; C.G. Mathew; P. Ellis; P.S. Hartley; C.D. Karabus The clinical, haematological and biosynthetic features of subjects with Hb E variants are described. An association with red cell hypochromia and microcytosis was confirmed, although this was not invariable in Hb E...
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Journal Articles

Combinations of Three Different Forms of α-Thalassemia in a Large Indian Family from Durban, South Africa: Hematological Observations

Subject Area:
Hematology , Oncology
You-jun Fei, Jin-cai Liu, Vinod B. Jogessar, Karyn R Westermeyer, Roshini Bridgemohan, Titus H J. Huisman
Journal: Acta Haematologica
Acta Haematol (1992) 87 (1-2): 11–15.
https://doi.org/10.1159/000204706
Published Online: 19 February 2009
... was homozygous for this deletion, and 1 was a compound hetero-zygote [-α(-3.7 kb/-α(-4.2 kb)]. Hematological and hemoglobin composition data indicated a moderate anemia in all 7 patients with Hb H disease with severe microcytosis and hypochromia, no elevation of γ-chain synthesis, low levels of Hb A 2 (0.3-0.7...
View article titled, Combinations of Three Different Forms of α-Thalassemia in a Large Indian Family from Durban, South Africa: Hematological Observations
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Journal Articles

Hb H Disease Caused by a Homozygosity for the AATAAA→ AATAAG Mutation in the Polyadenylation Site of the α2-Globin Gene: Hematological Observations

Subject Area:
Hematology , Oncology
You-Jun Fei, Reyhan Öner, Gulsen Bözkurt, Li-Hao Gu, Çigdem Altay, Aytemiz Gurgey, Slaheddine Fattoum, Erol Baysal, Titus H.J. Huisman
Journal: Acta Haematologica
Acta Haematol (1992) 88 (2-3): 82–85.
https://doi.org/10.1159/000204657
Published Online: 18 February 2009
... data with those of Hb H patients having other types of α-thalassemia determinants. All 7 patients exhibited moderate anemia with microcytosis and hypochromia being similar to that observed in the other patients. Relatives with a heterozygosity for this mutation are borderline microcytic and hy...
View article titled, Hb H Disease Caused by a Homozygosity for the AATAAA→ AATAAG Mutation in the Polyadenylation Site of the α2-Globin Gene: Hematological Observations
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