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Keywords: HFE
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Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2015) 133 (2): 155–161.
Published Online: 26 September 2014
...Eleanor Ryan; John D. Ryan; Jennifer Russell; Barbara Coughlan; Harold Tjalsma; Dorine W. Swinkels; Stephen Stewart; John P. Crowe Background/Aims: Innately low hepcidin levels lead to iron overload in HFE -associated hereditary haemochromatosis. Methods: This study compared hepcidin and non...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2009) 122 (2-3): 134–139.
Published Online: 10 November 2009
... therapy although a randomized trial of phlebotomy versus no treatment has never been reported. Since the discovery of the HFE gene in 1996, it has been possible to predict the risk of developing iron overload by a simple blood test to detect C282Y homozygotes of the HFE gene. The application...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2000) 102 (3): 152–156.
Published Online: 17 November 2004
... in the HFE gene related to hereditary haemochromatosis (Cys282Tyr and His63Asp) provided an opportunity to test whether they are associated with hepatic iron accumulation and the activity and severity of liver disease in hepatitis C virus (HCV) infection. We investigated the prevalence of HFE mutations...