.... Folic acid Leukemia Leukocyte proliferation Methionine synthetase A cta Haemat. 49: 200-210 (1973) Die Aktivität der Methionin-Synthetase (5-Methyl-5,6,7,8-tetrahydrofolsäure: Homocystein Methyltransferase) als Proliferationsparameter in wachsenden Zellen1 H. Sauer, K. W ilms, W. Wilmanns und L. J...

...George R. Honig; George Mason; Loyda N. Vida Folic acid deficiency has been reported to produce a substantial change in the ratio of hemoglobin S to hemoglobin A in the blood of individuals having sickle cell trait. Synthesis of the specific β -chains of these hemoglobins was studied before...

...R. Corrocher; M.L. Pachor; L.M. Bambara; A. Ambrosetti; G. DeSandre Folic acid binding protein (FABP) has been measured in the supernatant of leukocytes of 12 patients affected with chronic granulocytic leukaemia (CGL). The folate binding capacity ranged from 1.37 to 697.52 pg/mg protein, showing...

...Mitchell Rubinoff; Ruth Abramson; Carol Schreiber; Samuel Waxman Folic acid ( 3 H-pteroylglutamic acid or 75 Se-selenofolate) administered free or bound to folate-binding protein (FABP) was rapidly cleared from the plasma but the plasma survival when bound to FABP was longer than unbound during...

...) and in cirrhosis (p < 0.05), whereas only in the last case a reduced UFBC was present (p < 0.05). When serum from patients with acute hepatitis was eluted on Sephadex G-200 after incubation with radioactive folic acid (500 pg), two main peaks were observed, one in the exclusion peak of protein and the second...

... leukemia (AML). The membrane preparations from liver and from leukemic leukocytes were shown to bind tritiated folic acid. The membranes from normal leukocytes and erythrocytes did not show this binding capacity. The membrane preparation from liver and CGL leukocytes showed two peaks of binding eluting...

... folate but a normal blood count were treated with vitamin B 12 and folic acid for 3 months. Bone marrow deoxyuridine supression was abnormal in 3 of these 17 patients, 2 of whom also had megaloblastic change in the marrow. With treatment, the MCV fell in 13 of the 17, and the average MCV fell from 90.5...