...Shengchen Ge; Yuqing Luo; Rujiao Dong; Xiaoli Guo; Mingshan Wang; Yi Chen The objective of this study was to explore the molecular defects in two Chinese families with hypodysfibrinogenemia. The coagulation method and immunoturbidimetric method were used to detect plasma fibrinogen activity...

...Abdel Rahim Mahmoud Muddathir; Mozfar Idrees Abd Alla; Omar F. Khabour Cigarette smoking has been shown to be associated with changes in coagulation factors in the circulation and the subsequent thrombosis development. In this study, the impact of waterpipe smoking on the levels of fibrinogen...

... time intervals and subjected to standard (25°C) and cooled centrifugation (2–4°C). Subsequently, the prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT), fibrinogen, and D-dimer values were determined in runs with the same lot numbers in the same...

... and suspected DIC in West China Hospital between 2011 and 2015 were included in this study. We evaluated via univariate and multivariate analyses the diagnostic biomarkers, and the cutoff levels used in the CDSS, except those for fibrinogen, were found to be valid. In subgroup analyses, the value of fibrinogen...

... AJ, Saxe D, Simon MI, McBride OW, Crabtree GR: Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion. Proc Natl Acad Sci USA 1985;82:2344-2348. 3. Xu W, Chung DW, Davie EW: The assembly of human fibrinogen. J Biol Chem...

... of a single small dose of factor VIII (1 U/kg) or IX (2 U/kg) or fibrinogen (15 mg/kg) which did not improve the clotting disorder corrected the permeability for at least 3 days. The induction of a severe clotting disorder by heparin administration in man and by anticoagulant treatment in rabbits did...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. α 1 -Antitrypsin α 2 -Macroglobulin Antithrombin III Blood coagulation Cl inactivator Fibrinogen Fibrinolysis...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Blood coagulation Clot dispersion Factor XIII Fibrinogen Fibrin stabilization Fibrin urea dispersion Acta hacmat...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Plasminogen activator 125 I Fibrinogen Acta haemat. 60: 243-249...

...D. Ogston; W.D. Ogston The levels of components of the fibrinolytic enzyme system in 7 patients with anorexia nervosa were compared with those of healthy young women. Plasminogen activator levels were significantly higher and the mean fibrinogen concentration was lower in the anorexia nervosa...

... involved in the neutralization of thrombin, we studied the behaviour of this inhibitor in 14 ALL patients treated with a protocol including a 14-day course of L -asparaginase. A significant but transient fall of biological and immunological antithrombin III and a concomitant reduction of fibrinogen were...

.... The prothrombin and proconvertin (P&P), plasma antithrombin III (AT-III), and factor VIII related antigen increased significantly, while the activated partial thromboplastin time (APTT), fibrinogen and plasminogen decreased significantly upon Prednisone treatment. Investigations on fibrinolysis were...

...Toshio Shigekiyo; Masaaki Kosaka; Yasumi Shintani; Hiroyuki Azuma; Yasuhiko Iishi; Shiro Saito The mechanism of inhibition of fibrin monomer polymerization was studied in a patient with primary amyloidosis. Thrombin and reptilase times of the patient’s purified fibrinogen (Fbg) were remarkably...

.../fibrinogen degradation products (FDP) in serum. The assay of FDP was performed on serum samples prepared in test tubes containing 5 U/ml thrombin (final concentration) by a method based on latex agglutination using antifibrinogen antibodies, and the levels of D dimer in plasma were determined by a newly...

...Norihiko Amemiya; Yutaka Yatomi; Takeshi Endo; Asako Mizoe; Masumi Yoda-Endo; Tsutomu Yuminamochi; Masayuki Yamamoto; Yoshiro Matsumoto; Yukio Ozaki; Shoji Kume The present report concerns a case of hepatocellular carcinoma (HCC) with marked hyperfibrinogenemia. The plasma fibrinogen level reached...

... that allows them to become both the nidus and the stimulus for the precipitation of a meshwork of fibrin. The interactions between platelets and exposed collagen in the damaged vessel wall, plasma and platelet von Willebrand factor, and plasma and platelet fibrinogen can all be considered ‘adhesive...

... had high paraprotein concentration (85.75 g/l) and prolonged thrombin time (76.8 s), activated partial thromboplastin time (39.5 s), prothrombin time (23.5 s) and reptilase time (72.0 s). The fibrinogen level was increased. The fibrin polymerization induced by both thrombin and reptilase was impaired...

...Hyun Kyung Kim; Dong Soon Lee; Seong-Ho Kang; Jin Q Kim; Seonyang Park; Han-Ik Cho Although the presence of decreased plasma fibrinogen has been regarded as an indicator of ongoing disseminated intravascular coagulation (DIC), fibrinogen, which is one of the acute phase reactants, is often...