... subjects with a ferritin level within the sex-based normal range and only 4/39 had ferritin >1,000 ng/ml. Left ventricular (LV) and left atrial dilatation was common, but LV ejection fraction was normal (≥55%) in all subjects. Age was positively correlated with log ferritin in the 27 nontransfused...

...-R), several new prognostic variables are included, i.e. age, Eastern Cooperative Oncology Group performance score (ECOG PS), serum ferritin and lactate dehydrogenase. Chinese with MDS offer a unique opportunity to distinguish the prognostic impacts of haemoglobin (HGB) concentration, red blood cell...

... a combined administration of deferoxamine and deferiprone for 7.0 ± 1.3 years. Amidst a large number of variables examined, ferritin levels and delayed onset of chelation therapy were the only predictors of pulmonary hypertension. Conclusion: Pulmonary hypertension in β-thalassemia major is relatively...

... with SCD is due to primary testicular failure or secondary pituitary/hypothalamic dysfunction and assess the association between hypogonadism and serum ferritin levels. Hormonal assessment for serum concentrations of testosterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH) was done...

.... Treatment with subcutaneous infusions of desferrioxamine (DFO) had started when he was 10 years old. During the 6-month DFX treatment, serum ferritin levels progressively increased from 600 to 2,700 ng/ml despite progressive DFX dose adjustments. This paradoxically abnormal ferritin levels required drug...

... stores, plasma iron increased with the addition of 22.5 mg/day. These studies indicate that iron absorption is an important determinant of the elevated plasma iron in IH and that the plasma iron tolerance test combined with the serum ferritin may be used to detect excessive absorption of iron. 5 08...

...Isaac Ben-Bassat; Bracha Ramot; Esther Aghai; Meir Djaldetti In view of the reported associations of Hodgkin’s disease and ferritin, an electron microscopic study of the peripheral blood lymphocytes of these patients was done. In 5 out of the 6 patients studied intracellular ferritin deposits were...

...J. Economidou; O. Augustaki; V. Georgiopoulou; H. Vrettou; S. Parcha; D. Loucopoulos Serum ferritin concentration was assessed in male and female pregnant and non-pregnant thalassaemia carriers and in normal subjects of both sexes. Low ferritin levels were found in 61% of non-pregnant and in 32...

...S. Fargion; M.T. Taddei; M.D. Cappellini; A. Piperno; G. Fiorelli Serum iron, transferrin saturation, serum ferritin and urinary iron excretion have been tested in a group of Italian subjects with beta-thalassemia trait. A number of these subjects, mostly men, had signs of increased iron load...

...J. Oertel; M. Stephan; M. Kastner It has been found possible to test ferritin concentrations in the reticulum and hemopoietic cells from human bone marrow by an immunoradiometric assay. Ferritin concentration in healthy test persons amounts to 0.92 ± 0.38 ng/ μg protein in the reticulum and 0.084...

...F. Madanat; M. El-Khateeb; M. Tarawaneh; S. Hijazi The value of serum ferritin in assessing iron status was studied in 192 preschool age children between the ages of 3 and 60 months. Children were considered to have iron deficiency if the transferrin saturation was less than 16% and the peripheral...

...A. Piperno; M.T. Taddei; M. Sampietro; S. Fargion; P. Arosio; G. Fiorelli Basic ferritin (liver-type) was measured in erythrocytes of subjects with α - and β -thalassemia trait, thalassemia intermedia and Cooley’s disease, and compared with normals and patients with abnormal iron metabolism without...

... < 0.05); ACD subjects also had lower values although the difference was not significant (p > 0.05). MPO scores (MPO staining) were significantly lower in IDA and ACD subjects than in the healthy control group (p < 0.05). A significant positive correlation was noted between ferritin (R = 0.40...

...J.B. Porter; E.R. Huehns The relationship between the number of units of blood transfused and indicators of iron status in 37 patients with sickle cell anaemia (Hb SS), SC disease (Hb SC) or S β -thalassaemia has been studied. The correlation coefficient between serum ferritin and the number...

... parenterally or intragastrically to an iron-loaded rabbit caused no increase in Cu, Zn, Ca or Mg urinary excretion. Iron mobilisation was also observed following the incubation of the chelators with ferritin and haemosiderin but not with haemoglobin. Desferrioxamine under the same conditions caused...

...M. de Martino; M.E. Rossi; M. Resti; C. Vullo; A. Víerucci Superoxide anion production in resting and PMA- or zymosan-stimulated neutrophils was evaluated in 21 β -thalassemia patients. The results were correlated with ferritin values, hepatitis B virus serum markers, liver pathology...

...R. Navone; L. Azzoni; G. Valente In 340 bone marrow biopsies we compared ferritin, stained with an immunoperoxidase method, with hemosiderin, stained with Perls’ reaction. Ferritin and hemosiderin showed the same distribution in reti-culoendothelial cells. All the Perls-positive cases (n = 177...

...G. Ricci; M. Masotti; De Paoli Vitali; M. Vedovato; G.Z. Zanotti We studied 18 well-trained male long-distance runners during the basal training. Haematologic parameters, serum iron and ferritin, red cell 2,3-diphosphoglycerate (2,3-DPG) and creatine contents, serum erythropoietin were investigated...

... of microcytic ( < 60 fl) and/or hypochromic ( < 28 g·dl -1 ) red blood cells are determined. Of 472 elderly patients investigated, 100 (21%) were found to have iron deficiency (plasma ferritin ≤45 ng·ml -1 ). Less than two-thirds of patients with iron-deficient erythropoiesis (anaemia or microcytosis) had...

... variables, they were monitored for serum ferritin levels at 2-month intervals and hepatic iron concentrations in liver tissues were determined at the beginning and the 6th month of therapy. The severity of hepatic damage was graded according to the Knodell hepatic activity index and the fibrosis...