... diagnostic tools frequently used to differentiate between these conditions: factor VIII (FVIII) levels and the International Society on Thrombosis and Hemostasis (ISTH) DIC score. Methods: To this end, we conducted a retrospective chart review of patients with DIC, liver disease, or both. Multiple logistic...

...Inga Hegemann; Karin Koch; Wan Hui Ong Clausen; Mirella Ezban; Brigitte Brand-Staufer N8-GP (ESPEROCT®; turoctocog alfa pegol; Novo Nordisk A/S, Bagsvaerd, Denmark) is an extended half-life recombinant factor VIII (FVIII) molecule. FVIII-deficient plasma spiked with N8-GP can be accurately measured...

... in the coagulation parameters von Willebrand factor antigen (VWF:Ag), von Willebrand ristocetin cofactor (VWF:RCo), and Factor VIII activity (FVIII:C) during pregnancy in patients with VWD. In total, 44 pregnancies of 38 patients were assessed (VWD type 1 n = 32, type 2A n = 3, type 2B n = 1, type 2 subtype...

..., factor VII (FVII), and factor VIII (FVIII) was investigated. In addition, the effects of waterpipe smoking were compared to those of cigarette smoking and never smokers. A total of 80 male smokers (40 cigarette smokers and 40 waterpipe smokers) and 40 apparently healthy never smokers were recruited...

..., instructions or products referred to in the content or advertisements. Angiohaemophilia Aspirin tolerance test Bleeding disorders Factor VIII Platelet aggregation Von Willebrand’s disease Acta Haemat. 52: 29-39 (1974) Von Willebrand s Disease in Italy A Study of 13 Families from a Small Area...

... VIII level of about 15% we observed a marked increase of capillary permeability. On the contrary, 2 patients with a congenital lack of factor V, 2 cases of von Willebrand’s disease with a factor VIII level of about 50% and 3 subjects with ITP showed a normal capillary permeability. The administration...

...A. Girolami; Dal Bo Zanon; F. Fabris; R. Franzoso A patient with combined factor VII and factor VIII deficiency is discussed. The propositus is a 21-year-old male who presented a mild bleeding tendency. The patient appears to be a hemophilia and at the same time heterozygote for factor VII...

... received factor VIII cover, during and after a laparatomy. The possible hereditary transmission pattern of the combined defect is discussed. 25 09 1979 11 10 1979 3 3 2009 © 1980 S. Karger AG, Basel 1980 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

...Hugo Zwahlen; Eugene A. Beck Possible effects and side-effects of ‘factor VIII inhibitor bypassing activity (FEIBA)’ were tested on 7 haemophiliacs with high-titre antibody to factor VIII (resistant haemophilia). FEIBA was administered both to hospitalised patients and as part of a home therapy...

.... Coagulation Factor VIII Platelet aggregation Ristocetin-cofactor Sickle cell disease Actahaemat. 77: 156-160(1987) 1987 S. Karger A G , Basel 0001-5792/87/0773-0156 S 2.75/0 Coagulation Changes in Sickle Cell Disease in Early Childhood M.A. Babikera, E.F. Ashonga, H. Bahakima, A.M.A. Gaderb Departments...

...I. Melamed; M. Djaldetti; H. Joshua; U. Seligsohn Associations of hereditary abnormalities of the factor VIII complex and hereditary platelet disorders have previously been reported in 12 families. Another family is reported in which 6 members had a bleeding tendency and thrombocytopathy...

...Kenji Niiya; Ichiro Kubonishi; Hirokuni Taguchi; Isao Miyoshi Two family members (daughter and mother) with a bleeding disorder showed prolonged bleeding time and activated partial thromboplastin time associated with decreased plasma levels of factor VIII procoagulant activity, factor VIII-related...

...John J. Gadarowski, Jr.; Emily E. Czapek; John D. Ontiveros; Jose L. Pedraza A factor IX inhibitor was assayed by using a modification of the Bethesda assay for factor VIII inhibitors. The incubation time was shortened to 15 min. A screening method using the activated partial thromboplastin time...

... coagulation tests showed a prolongation of activated partial thromboplastin time associated with a marked reduction of factor VIII activity (VIII :C 5%). Other deficiencies of blood coagulation factors, especially von Willebrand factor, were excluded. Measurement of factor VIII inhibitor revealed an activity...

...Uri P. Martinowitz; Sam Schulman Continuous infusions of factor VIII have proved feasible in patients with hemophilia A, and the hemostatic efficacy has sometimes been superior to that of repeated bolus injections of factor VIII. Avoiding dangerously low trough levels by maintaining a constant...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Factor VIII Hemophilia A Nursing...

... of distribution at steady state (V ss ). Hemophilia A is an X-chromosome (Xq28)-linked recessive genetic coagulation disorder caused by a factor VIII (FVIII) deficiency resulting in hemorrhages of variable degrees. The mainstay of hemophilia A care consists of adequate replacement of the deficient...

...Ayodele Ayoola; Wajahath Mohsini; Sein Aung Background: Acquired factor VIII inhibitor is an antibody formed against FVIII and seen in patients without FVIII replacement therapy. This entity has been associated with both autoimmune disease and infections. Case Study: We report the case of a 65-year...

...Farzaneh Towfighi; Soheila Gharagozlou; Ramazan Ali Sharifian; Anoushirvan Kazemnejad; Khadijeh Esmailzadeh; Mohammad Reza Managhchi; Fazel Shokri Factor VIII (FVIII) inhibitor antibodies are produced against functional epitopes of FVIII in about 30% of severe hemophilia A patients leading...

...Kanjaksha Ghosh; Shrimati Shetty; Anil Pathare; Dipika Mohanty Haemophilia patients with inhibitors pose a formidable challenge for patient management. This is particularly problematic in developing countries, where porcine factor VIII, FEIBA, factor VIIa or immunoadsorption column are generally...