... to in the content or advertisements. Factor VII deficiency Compound heterozygosity Bleeding Factor VII (FVII) deficiency is the most frequent defect encountered among the rare clotting disorders. The defect has been described all over the world [ 1 ], Argentina included [ 2-6 ]. The two mutations...

...Balraj Singh; Varun Modi; Parminder Kaur; Gunwant Guron; Michael Maroules Thrombotic events in bleeding disorders such as hemophilia A or B, Von Willebrand disease, afibrinogenemia, factor VII deficiency, and factor XI deficiency are rare but have been reported. These events usually occur...

...A. Girolami; P. Scorza; A. Brunetti; C. Morgagni; G. Santini Two new cases of congenital factor VII deficiency are reported. They are two 7-year-old boys belonging to two different kindreds. The main clinical features were: bleeding from the gums, epitaxis (one patient), easy bruising, melena...

...T. Shifter; I. Machtey; D. Creter An Israeli family of Persian origin was investigated for factor VII deficiency. The proposita, derived from a consanguineous marriage, had repeated thrombophlebitis attacks, pulmonary embolism and rectal bleeding. The family studied and the proposita had low factor...

...Piedad Villa; Amparo Estellés; José Luis Pérez-Requejo; Francisco España; Justo Aznar A family with inherited factor VII deficiency is described. The propositus is a 9-year-old girl with chronic haemorrhagic history of epistaxis and bleeding after tooth extractions. Her factor VII coagulant...

... factor VII deficiency. Haemolysis was mild in the propositus and the RBC membrane leak included a marked increase in passive permeability to Na + and K + . This was associated with an increase in active Na + , K + -pump activity and in the ouabain-resistant fluxes: Na + , K + -cotransport and Na + , Li...

... to in the content or advertisements. Coagulation F7 gene Factor VII deficiency Molecular defect Mutagenesis Coagulation factor VII (FVII) is a vitamin-K-dependent plasma glycoprotein [ 1 ]. It is synthesized in the liver and circulates in the blood as an inactive zymogen. Upon vascular injury...