...Leonard Naymagon; Douglas Tremblay; John Mascarenhas Data supporting the use of etoposide-based therapy in hemophagocytic lymphohistiocytosis (HLH) arise largely from pediatric studies. There is a lack of comparable data among adult patients with secondary HLH. We conducted a retrospective study...

...-stimulating factor (FLAG) in combination with etoposide (FLAG-Eto) in 36 patients. The complete remission rate (CR) was 25.7% with a median overall survival of 6 months (95% CI 4.5–7.7). The median disease-free survival for CR/CRi/MLFS (CR/CR with incomplete he­matological recovery/morphologic leukemia-free...

...Ibrahim Aldoss; Lingyun Ji; Mintallah Haider; Vinod Pullarkat We retrospectively reviewed the outcome of 20 consecutive subjects with refractory/relapsed acute myeloid leukemia (AML; 9 refractory and 11 relapsed) treated at our institution with a fludarabine, cytarabine and etoposide (FCE) salvage...

... days. 61 were treated with the same regimen but 6-thioguanine was replaced by etoposide. Complete remission was achieved in 57 and 72% of patients, respectively (p = 0.06). In leukemias with monocytic phenotype (M4-M5), the remission rate was significantly higher with the etoposide-containing regimen...

...Nozomi Niitsu; Masanori Umeda Twenty-eight patients (14 with relapsing and 14 with refractory non-Hodg-kin’s lymphoma; NHL) were treated with a combination of CACE chemotherapy (cytosine arabinoside, carboplatin, and etoposide) and recombinant granulocyte colony-stimulating factor (G-CSF...

...Takahiro Okamoto; Yasuo Nishimura; Shinji Yamada; Shu Yamada; Tohru Itoh; Ako Mori; Kaname Saheki; Masaya Okada; Hiroyuki Takatsuka; Hiroshi Wada; Amane Tamura; Yoshihiro Fujimori; Eizo Kakishita It is known that the topoisomerase II inhibitors, MST-16 (sobuzoxane) and VP-16 (etoposide...