... wAIHA patients and 8 healthy controls were isolated from peripheral blood and cultured for 3 days with or without the presence of hUC-MSCs; PBMCs were co-cultured with hUC-MSCs using Transwell assays. The supernatant cytokine levels were measured after culture through AimPlex Multiple Immunoassays...

... between MS components, inflammatory cytokines, and the development of MM, and some drugs used in the treatment of MS such as statins and metformin may improve outcomes in MM. Cytokines Lipids Metabolic syndrome Metformin Myeloma Obesity Paraprotein Statins 4 09 2019 11 01 2020...

...Matthew S. Karafin; Pippa Simpson; Joshua J. Field Chronic pain affects 50% of adults with sickle cell disease (SCD). Although inflammation is thought to contribute to the pathogenesis of chronic pain, no studies have examined the differences in circulating cytokines between patients with SCD...

... to in the content or advertisements. 2012 Chemokines Cytokines Interleukin-6 Multiple myeloma Promyelocytic leukemia Multiple myeloma (MM) is a malignant neoplasm of plasma cells that is incurable because myeloma cells are difficult to eradicate by current therapeutic approaches. MM occurs most...

... causes of anemia. Changes to bone marrow microenvironment could contribute to apoptotic events. This study examined the effects of cytokines interleukin-1β, tumor necrosis factor-α and interferon-γ on apoptosis of β-thal/HbE erythroid progenitor cells in vitro, including nitric oxide-mediated apoptotic...

... and trafficking is different in SCD compared to other hemoglobinopathies. The high levels of inflammatory cytokines in SCD may enhance macrophage/reticuloendothelial cell iron and/or renal cell iron retention. This makes the tissues that retain iron different in SCD, and thus the organs that fail in SCD...

.... Cytokines Interferons Neoplasms Symposium. New Therapeutical Trends with Immunomodulating Agents in Hematologic-Oncologic D i s e a s e s Hcmato-Oncology and Hemato-Immunology. Proc. 2nd Int. Conf., Catania 1986 Acta haemat. 78:suppl. I, pp. 64-69 (1987...

... to in the content or advertisements. Chronic granulomatous disease Cytokines Granulomatous cheilitis Phagocytes Respiratory burst Acta Haematol 1990;84:49-56 (g) 1990 S. Karger AG. Basel 0001 -5792/90/0841 -0049 S 2.75/0 Chronic Granulomatous Disease in an Adult Female with Granulomatous Cheilitis...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cytokines Erythropoietin Hematology Hematopoietic growth factors Oncology Acta Haematol 1991;86:138-147 Clinical Role of Colony Stimulating Factors W. Brugger, F.M...

... Cytokines Gene expression Hematopoiesis Hematopoietic growth factor Myelosuppression 19 2 2009 Acta Haematol 1991;86:148-154 The Role of Interleukin-1 in Hematopoiesis W.E. Fibbe, R. Willemze Department of Hematology, University Medical Center Leiden, The Netherlands © 1991 S. K arger A G...

... to in the content or advertisements. Acute myelogenous leukemia Cytokines Cytosine arabinoside Granulocyte colony-stimulating factor Proliferating cell nuclear antigen Transferrin receptor Case Report Acta Haematol 1993;89:144-148 Hideo Gotoa Chihiro Shimazakia Toshiyuki Hirataa Eishi Ashiharaa...

... these cytokines were administered with PSK compared to when the cytokines were used individually. In vitro colony assay revealed that the combination of PSK and any of GM-CSF, IL·3 or stem cell factor (SCF) showed a greater increase in colony numbers than when these materials were administered individually...

...Maria Alessandra Santucci; Roberto Massimo Lemoli; Sante Tura Peripheral blood (PB) mobilization of hematopoietic progenitors, presently regarded as an alternative source of cells intended for autologous or allogeneic bone marrow (BM) transplantation, supports a role for cytokines in the regulated...

..., AIDS-related lymphomagenesis is characterized by activation of protooncogenes, inactivation of tumor suppressor genes, viral infection of the tumor clone, and deregulated cytokine production. Distinct AIDS-NHL types associate with specific molecular pathways. The first pathogenetic pathway clusters...

... of hematopoietic progenitors, whereas in virus-infected cell lines production of both normal and virus-infected progenitors was suppressed. Expression of cytokine genes in stromal cell lines was also examined. All cell lines expressed equivalent levels of transcripts for interleukin (IL)-1β IL-2, IL-3, IL-6, IL-7...

... production. Secondary or reactive thrombocytosis can be observed in a number of clinical circumstances, and may be related to persistent overproduction of some thrombocytopoietic factors acting on megakaryocytes. Several cytokines, including IL-6, IL-1 and IL-4 have been shown to act alone or in concert...

...-type myeloma Y = 4.25X + 4.75. For the purpose of analyzing in detail the granular lymphocyte behavior, two-color analyses of peripheral blood mononuclear cells and the serum levels of cytokines were performed. The absolute number of CD3+ cells, CD4+CD45RA+ cells and CD4+CD29+ cells was lower...

..., and polyclonal hematopoiesis was not observed. Donor origin was established by the Y chromosome probe. These results support the clonal succession model of hematopoiesis. Gene transfer Stromal microenvironment Cytokines Hematopoietic stem cells © 1996 S. Karger AG, Basel 1996 Copyright / Drug...

... mediates most of the hematopoietic effects exerted by SP and NK-A partly through the induction of cytokines. The proliferative effects of SP correlate with the induction of positive hematopoietic growth factors such as IL-3, IL-6, GM-CSF and c-kit ligand and the inhibitory effects by NK-A correlate...

... of cytokines and differentiated into myeloid cells with slight proliferation. The results of immunohistochemical experiments suggested activation of FAK and AKT in hematopoietic cells attached to osteoblasts. When stem cell factor, Flt3-L, and IL-3 were added to the coculture system, each cytokine...