... digested DNA from both leukemic blasts and monocytoid cells had the same rearranged band of IgH. Thus, an identical clonality of monocytoid cells, temporally appearing after chemotherapies and leukemic lymphoblasts, was determined in this patient with CD13 + ALL. 7 03 1991 5 09 1991 19 2...

... are composed of an admixture of neoplastic clonal B cells and reactive T cells which occasionally are very prominent in the histological picture. Infectious mononucleosis, anaplastic large cell lymphoma, composite lymphoma and Hodgkin’s disease, all share many similarities and may actually represent...

... understanding of the molecular pathology of mastocytosis. First, systemic mastocytosis has been found to be associated with activating codon 816 mutations of the c-kit gene. Second, this mutation was used as a tracking marker to elucidate the clonal nature of mastocytosis. These findings have resulted...

...Susanne Walburg Braun; Helmut Heinrich Gerhartz; Helga Maria Schmetzer We have already shown that cytokine cocktails (IL-1β, IL-3, IL-6, SCF, GM-CSF) and/or lymphokine-activated killer (LAK) cells can reduce the amounts of clonal, CD34-positive mononuclear bone marrow cells (BM-MNC) in acute...

...H.M. Schmetzer; S. Braun; D. Wiesner; T. Duell; H.H. Gerhartz; J. Mittermueller At diagnosis, clonal gene rearrangement probes [retinoic acid receptor (RAR)-α, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-β, myeloid lymphoid leukemia (MLL) or cytokine genes...

..., instructions or products referred to in the content or advertisements. Clonality Myelodysplastic syndrome Phosphoglycerate kinase X chromosome Myelodysplastic syndrome (MDS) is a disorder characterized by ineffective and dysplastic hematopoiesis, and the dysplasia is commonly manifested...