...Shao-xue Ding; Tong Chen; Ting Wang; Chun-yan Liu; Wen-li Lu; Rong Fu Objectives: This meta-analysis aimed to evaluate the risk of clonal evolution of granulocyte colony-stimulating factor (G-CSF) in acquired aplastic anemia (AA), and whether the use of G-CSF increases the occurrence of secondary...

..., Rome Key Words. Blastic transformation Clonal evolution Sex chromosomes Y chromosome Abstract. 2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Banding Bladder Clonal evolution Marker chromosomesMyeloblastic transformation Myelofibrosis Neutrophil alkaline...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Clonal evolution Multiple transformations Survival, extended Acta haemat. 76: 173-175(1986) © I986S . Karger AG. Basel OOOI-5792/86/0763-0173 $ 2.75/0 Multiple Blastic...

...) was detected. On referral for bone marrow transplant (BMT) he was found to be in accelerated phase with clonal evolution in three cell lines inv(3)(q21q26); inv(3)(q), i(17q); inv(3q)+8. Molecular investigation revealed a breakpoint on chromosome 22 within the breakpoint cluster region (bcr) similar...

... acceleration. Both of these secondary clonal phenomena responded to IFN-α dose escalation. The case illustrates the dose dependence of CML responses to IFN-α. The phenomenon of clonal evolution is discussed in the context of this patient’s disease. 11 09 1989 24 09 1989 20 2 2009 © 1990 S...

... and cytogenetic examination showed clonal evolution by the appearance of additional numerical aberrations in addition to the ring chromosome [46,XY,r(1),+8,–21/45,XY,r(1),+8,–21,–22/46, XY]. Intensive chemotherapy and radiotherapy was applied to induce remission in preparation for allogeneic bone marrow...

... Clonal evolution Hairy-cell leukemia Immunoglobulin gene rearrangement Leukemic cells of hairy-cell leukemia (HCL) are clonally proliferating B-lymphoid cells with clonal rearrangements of genes for immunoglobulin chains in almost all patients [ 1 ]. Rearrangements of the immunoglobulin genes...