...Kanji Miyazaki; Kenshi Suzuki Chronic myelomonocytic leukemia (CMML) is a clonal hematological disease characterized by the presence of peripheral blood monocytosis and bone marrow dysplasia. Double minute chromosomes (dmin) are rare and intracytoplasmic crystalline inclusions are very rare...

...Joan-Lluis Vives-Corrons; Lourdes Florensa; Josep Muncunill; Benet Nomdedeu; Ciril Rozman A congenital erythrocyte pyruvate kinase (PK) deficiency was found in a 72-year-old female patient with chronic myelomonocytic leukemia (CMML). Erythrocyte PK deficiency was associated with an increase...

... the proliferation of the normal granulocytopoiesis did not affect the granulocytopoiesis of 7 chronic myeloid and 2 chronic myelomonocytic leukemias at the same dose level. In contrast to these chronic leukemias, blast proliferation of 4 acute myeloid and monocytic leukemias was greatly depressed not only for 6 h...

...Noriko Takuwa; Shiro Kanegasaki; Shigetaka Asano; Toshio Tomita; Emiko Nakayama; Noriharu Sato; Tamiko Shinohara; Shiro Miwa The maturation process of leukemic myelomonocytoid cells derived from peripheral blood of two typical cases of chronic myelomonocytic leukemia was investigated in vitro...

...E.H. Rao; G. Cesarman; M. Coleman; S. Acaron; R.S. Verma A 27-year-old male developed massive generalized lymphadenopathy with chronic myelomonocytic leukemia (CMML) presenting as extramedullary blast crisis mimicking a lymphocytic lymphoma. On presentation, a consistent chromosomal abnormality...

...Kohsuke Yanagisawa; Kyouko Kishimoto; Takahiko Horiuchi; Kiyonori Takada; Masaki Yasukawa; Shigeru Fujita We examined the effects of interleukin-4 (IL-4) on the growth of hematopoietic precursors from a patient with chronic myelomonocytic leukemia (CMMoL). In the chronic phase of the disease, IL-4...

..., atypical chronic myeloid leukemia and chronic myelomonocytic leukemia. Current classification often does not clearly separate these entities since they share many features, both clinically and hematologically. We report here a case that satisfies criteria for both chronic myelomonocytic leukemia...

...Myungshin Kim; Jihyang Lim; Ahwon Lee; Gyeongsin Park; Yonggoo Kim; Kyungja Han; Chang Suk Kang; Yoo-Jin Kim; Jeong-Sup Song We describe an unusual case of chronic myelomonocytic leukemia with severe eosinophilia having t(5;12)(q31;p13) with t(1;7)(q10;p10). The eosinophilic proliferation...

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...K.L. Bourantas; S. Tsiara; A. Panteli; C. Milionis; L. Christou Pleural effusion in 4 patients with chronic myelomonocytic leukemia (CMML) is described in this report. According to the literature, pleural effusion in CMML is a poorly understood and rare occurrence. Two of our patients presented...