...Kanji Miyazaki; Kenshi Suzuki Chronic myelomonocytic leukemia (CMML) is a clonal hematological disease characterized by the presence of peripheral blood monocytosis and bone marrow dysplasia. Double minute chromosomes (dmin) are rare and intracytoplasmic crystalline inclusions are very rare...

...Joan-Lluis Vives-Corrons; Lourdes Florensa; Josep Muncunill; Benet Nomdedeu; Ciril Rozman A congenital erythrocyte pyruvate kinase (PK) deficiency was found in a 72-year-old female patient with chronic myelomonocytic leukemia (CMML). Erythrocyte PK deficiency was associated with an increase...

... the proliferation of the normal granulocytopoiesis did not affect the granulocytopoiesis of 7 chronic myeloid and 2 chronic myelomonocytic leukemias at the same dose level. In contrast to these chronic leukemias, blast proliferation of 4 acute myeloid and monocytic leukemias was greatly depressed not only for 6 h...

...Noriko Takuwa; Shiro Kanegasaki; Shigetaka Asano; Toshio Tomita; Emiko Nakayama; Noriharu Sato; Tamiko Shinohara; Shiro Miwa The maturation process of leukemic myelomonocytoid cells derived from peripheral blood of two typical cases of chronic myelomonocytic leukemia was investigated in vitro...

...Kohsuke Yanagisawa; Kyouko Kishimoto; Takahiko Horiuchi; Kiyonori Takada; Masaki Yasukawa; Shigeru Fujita We examined the effects of interleukin-4 (IL-4) on the growth of hematopoietic precursors from a patient with chronic myelomonocytic leukemia (CMMoL). In the chronic phase of the disease, IL-4...

...E.H. Rao; G. Cesarman; M. Coleman; S. Acaron; R.S. Verma A 27-year-old male developed massive generalized lymphadenopathy with chronic myelomonocytic leukemia (CMML) presenting as extramedullary blast crisis mimicking a lymphocytic lymphoma. On presentation, a consistent chromosomal abnormality...

..., atypical chronic myeloid leukemia and chronic myelomonocytic leukemia. Current classification often does not clearly separate these entities since they share many features, both clinically and hematologically. We report here a case that satisfies criteria for both chronic myelomonocytic leukemia...

...Myungshin Kim; Jihyang Lim; Ahwon Lee; Gyeongsin Park; Yonggoo Kim; Kyungja Han; Chang Suk Kang; Yoo-Jin Kim; Jeong-Sup Song We describe an unusual case of chronic myelomonocytic leukemia with severe eosinophilia having t(5;12)(q31;p13) with t(1;7)(q10;p10). The eosinophilic proliferation...

.... These findings were compatible with chronic myelomonocytic leukemia. Moreover, due to his chromosome abnormality, our case supports the findings previously reported [ 1, 2 ]. Among all reported cases of trisomy 14, those with monocytosis account for 16.1% (5/31) [ 1, 2, 3, 4, 5 ]and those with thrombocytosis...

...K.L. Bourantas; S. Tsiara; A. Panteli; C. Milionis; L. Christou Pleural effusion in 4 patients with chronic myelomonocytic leukemia (CMML) is described in this report. According to the literature, pleural effusion in CMML is a poorly understood and rare occurrence. Two of our patients presented...