... of several well-defined chromosomal abnormalities such as t(8;21)(q22;q22), t(15;17)(q22;q12) and inv(16)(p13.1q22) or t(16;16)(p13.1q22) are a sufficient criterion for AML diagnosis, regardless of the number of blast cells. Approximately half of the patients diagnosed with AML have normal karyotype (NK...

... chronic myelofibrosis should be considered a separate entity. Also, it is possible that AAMM with trisomy of chromosome No. 8 and stormy clinical course may be a different entity from the acute myeloproliferative disorders associated with other chromosomal abnormalities. Acute Agnogenic Myeloid Metaplasia...

... to in the content or advertisements. Acute leukaemia Chromosomal abnormalities Elliptocytosis Myelodysplasia Schistocytosis Case Reports Acta haemat. 75: 174-177(1986) 0001 -5©79129/8866/S0.7K53ar-g0c1r7A4 G$ ,2.B7a5s/e0l Elliptocytosis and Schistocytosis in Myelodysplasia: Report of Two Cases J.L...

... Essentially similar chromosomal abnormalities were observed in the two cell lines. These were characterized by striking morphological aberrations such as elongation and despiralization (uncoiling or incomplete contraction), increased frequency of chromosome breakage and centromere spreading. Numerical...

... was comparable to that of patients having other chromosomal abnormalities or patients who were karyotypically normal, the median survival time was only 18 months (p < 0.02). Consequently, aggressive treatment such as early stem cell transplantation and so on is needed to improve their survival. 29 04...