... of adverse disease biology and limited tolerability of conventional chemotherapy. Summary: Here, we discuss recent data from clinical trials investigating new approaches for initial treatment of Philadelphia chromosome-negative ALL in older adults. These trials investigate the incorporation of novel agents...

... to in the content or advertisements. 2023 [email protected] 27 09 2023 6 11 2023 21 11 2023 Antibiotic prophylaxis Fluoroquinolones Acute leukemia Neutropenia Chemotherapy Therapy for acute leukemia (AL) requires the use of intensive remission induction chemotherapy...

... following treatment than in traditional chemotherapies. Future assessments of the incidence of SS among patients treated with novel therapies for AML and molecular studies of biopsy samples may help further explain this dermatologic adverse event and allow for earlier diagnosis and management...

... Group T-cell acute lymphoblastic leukemia (T-ALL) is a rare disease usually treated with intensive, high-dose consolidation chemotherapy followed by an allotransplant in a substantial number of patients. The data of the RALL-2009 study on 125 adult T-ALL patients suggest that similar total chemotherapy...

...Tali Siegal; Osnat Bairey Primary central nervous system (CNS) lymphoma is an aggressive brain tumor sensitive to chemotherapy and radiotherapy. Its incidence has increased in the elderly, and they account for the majority of patients. The median survival of patients older than 70 years did...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemotherapy Non-Hodgkin’s lymphoma Progression-free survival Toxicity...

.... Spine involvement and T/NK-cell phenotype are more frequent in Japanese than in Caucasian patients with PBL. Chemotherapy 18 F-fluorodeoxyglucose-positron emission tomography Primary bone lymphoma Radiotherapy Primary bone lymphoma (PBL) is a rare disease. PBL comprises less than 1...

... in treating NLPHL still needs clarification. Methods: We retrospectively reviewed the outcome of 23 patients with NLPHL treated with rituximab alone or in combination with chemotherapy and/or radiotherapy as part of their first- or second-line treatment. Results: The median follow-up of the whole group was 67...

... was supported by grants from the Swiss National Science Foundation (PP00P3_128461/1) and the Olga Mayenfisch Stiftung (both to M.S.). In conclusion, we could not detect an effect of SSRI or non-SSRI treatment on bleeding events in patients with severe thrombocytopenia induced by chemotherapy. SSRIs [e.g...

... outcome is unsatisfactory. We compared up-front allogeneic hematopoietic cell transplantation (HCT) to induction chemotherapy (IC) as an initial treatment in patients with s-AML arising from MDS. This retrospective study included 85 patients who were diagnosed with s-AML arising from MDS; 11 patients...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute leukemia (adult) Allogeneic bone marrow transplantation Chemotherapy Over half of adults with acute...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemotherapy Malignancy Radiotherapy Regardless of whether clinicians believe...

... = 11, 50%) and the most common histology was diffuse large B-cell lymphoma. 21 patients received chemotherapy as initial therapy and 16 received combined chemoradiation. 81.8% of the patients (n = 18) achieved complete remission. 5-year survival rate was 86.3% and overall survival was found...

... lymphoblastic leukemia is unsatisfactory in adults due to disease and patient-related factors and probably because adult chemotherapy regimens are weaker than pediatric protocols. Worries about inadequacy of adult regimens urged many hematologists, including us, to reconsider their routine treatment practices...

..., and the pathological examination revealed FL grade 2. She was treated with combination chemotherapy consisting of rituximab, cyclophosphamide, vincristine, doxorubicin, and prednisone (R-CHOP), and a complete response has been maintained. A 59-year-old woman visited our hospital because of edema in 2008...

... manifestations. 29 08 2011 26 10 2011 12 1 2012 In our case, even though the tumor was highly sensitive to chemotherapy, the response duration time was short, and the disease progressed rapidly after relapse with an overall survival time of 15 months. Review of the literature illustrates...

.... This report concerns the effect of cyclosporin A (CsA) on chemotherapy-refractory AITL. A 68-year-old female with AITL with systemic symptoms, such as high fever, skin rash andgeneralized lymphadenopathy, was initially treated with conventional cytotoxic chemotherapies using alkylators, anthracyclines...

... acute myeloid leukemias without erythroblastic and/or megakaryocytic dysplasia achieve complete remission and longer survival after classical chemotherapy 3 + 7 (English abstract). Vnitr Lek 2010;56:37–43. 27. Baldus CD, Liyanarachchi S, Mrózek K, Auer H, Tanner SM, Guimond M, Ruppert AS, Mohamed N...

.... We evaluated the prognostic significance of the pretreatment serum level of 15-kDa granulysin in patients with diffuse large B cell lymphoma (DLBCL). Patients and Methods: A retrospective analysis was conducted on 88 DLBCL patients treated homogeneously with standard chemotherapy. The granulysin...

... immunochemotherapy immediately after diagnosis was administered in 58 patients (post-rituximab era) and chemotherapy alone (CHOP) in 53 (pre-rituximab era). All patients received the CHOP chemotherapy regimen. Clinical characteristics at diagnosis are listed in table 1 . The median follow-up for CHOP- and R...