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Keywords: Cell proliferation
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Journal Articles

Apoptosis and Reduced Cell Proliferation of HL-60 Cell Line Caused by Human Telomerase Reverse Transcriptase Inhibition by siRNA

Subject Area:
Hematology , Oncology
Ebrahim Miri-Moghaddam, Abdolkhaleg Deezagi, Zahra Sohaila Soheili, Parvin Shariati
Journal: Acta Haematologica
Acta Haematol (2010) 124 (2): 72–78.
https://doi.org/10.1159/000314960
Published Online: 14 July 2010
.... In this study, the ability of short-interfering RNA (siRNA) to downregulate hTERT expression and its correlation with cell growth and apoptosis in the promyelocytic cell line HL-60 was evaluated. Materials and Methods: hTERT siRNA was designed and transfected to HL-60. hTERT mRNA expression, cell proliferation...
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Journal Articles

Current Concepts of Abnormal Stem Cell Proliferation in Human Disease

Subject Area:
Hematology , Oncology
William A. Robinson
Journal: Acta Haematologica
Acta Haematol (1979) 62 (5-6): 331–337.
https://doi.org/10.1159/000207598
Published Online: 03 March 2009
... cellular defects which do not allow cells to respond to these materials. The nature of the stem cell defects has not been defined. Similar mechanisms appear to exist in other human hematopoietic disorders in which abnormal stem cell proliferation is a major feature. Cell proliferation Stem cell...
View article titled, Current Concepts of Abnormal Stem <span class="search-highlight">Cell</span> <span class="search-highlight">Proliferation</span> in Human Disease
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Journal Articles

In vitro Biological Activities of the Haemopoietic Growth Factors: Implications for Their Clinical Use

Subject Area:
Hematology , Oncology
N.G. Testa
Journal: Acta Haematologica
Acta Haematol (1991) 86 (3): 122–127.
https://doi.org/10.1159/000204821
Published Online: 19 February 2009
...N.G. Testa The recent availability of several haemopoietic growth factors in purified recombinant form suitable for clinical use has prompted their use in haematology and oncology. The knowledge of their various effects in vitro on cell proliferation, differentiation and function...
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