... systemic autoimmune disease. Patients with AIMF present with cytopenias and autoantibodies, and have a distinctive nonclonal myelofibrosis on bone marrow examination. AIMF is distinguished from primary myelofibrosis by the absence of splenomegaly, eosinophilia, or basophilia, and the absence of abnormal...

..., the FXIII-specific activity turned out to be low. FXIII inhibitor and anti-FXIII-A subunit autoantibodies were detected by a 1:1 crossmixing test and immunoblot and immunochromatographic assays. She was therefore diagnosed with “definite AH13” and treated with plasma-derived FXIII concentrates to arrest...

...-occurrence of inhibitors to multiple coagulation factors is uncommon. These autoantibodies may induce spontaneous life-threatening bleeding in patients who have had no previous bleeding disorder. Herein, we present a patient with postpartum acquired FVIII and FIX inhibitors who developed intramuscular...

... to in the content or advertisements. Autoantibodies Erythrocyte membrane Haemolytic anaemias Osmotic fragility Acta haemat. 46: 60-63 (1971) Modifications de la résistance osmotique des hématies au cours des maladies hémolytiques par auto-anticorps1 J.-F. Stoltz, F. Streiff, C. V igneron, B. Genetet et...

... or the detection of leukocyte and platelet antibodies. Thrombocytopenic purpura was present in 6 patients, and in 2 of these since infancy. AHA may thus be a complex autoimmune syndrome that may involve leukocytes and platelets as well as erythrocytes, with synthesis of autoantibodies specific for different blood...

...S.R. Joshi; Y.S. Iyer; H.M. Bhatia 55 cases of autoimmune haemolytic anaemia with positive direct Coombs’ test were investigated for the nature of autoantibodies. The studies involved characterization of the autoantibodies on the basis of their thermal amplitude, serological specificity, nature...

... coating of the red cells. The IgM and IgG components could be separated. The cold autoantibodies were active at 30°C or above and often showed blood group specificity within the Ii system; specificity was not usually evident in the warm component. Haemolysins were found in 18 patients. Serologically...

..., instructions or products referred to in the content or advertisements. Anaemia, haemolytic, autoimmune Autoantibodies Haemoglobinuria, paroxysmal Acta haemat. 68: 268-277 (1982) Autoimmune Haemolysis Associated with Donath-Landsteiner Antibodies R. J. Sokol, S. Hewilt, Barbara K. Stamps Regional...

... sexes were equally affected. The incidence decreased from 1 in 188 × 10 3 in young males to 1 in 1,780 × 10 3 in children over 10. Cases were classified serologically. Of particular note was the frequency of Donath-Landsteiner haemolysis which equalled that due to warm autoantibodies; together...

... heterozygous for C 4 deficiency. Measurements of common autoantibody idiotypes may contribute to the understanding of the genetics of autoimmune diseases. They might be found useful in detecting healthy subjects prone to the development of an overt clinical state. 13 12 1985 24 03 1986 25 2...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Autoantibodies Autoimmunity Idiotypes, anti-idiotypes Actahaemat. 76: 95-100(1986) © 1986 S. Karger AG. Basel 0001...

...S. Sukenik; A.E. El-Roesner; Y. Shoenfeld The lupus anticoagulant (LA) is an acquired autoantibody of the IgG or IgM type that acts on platelet factor III, inhibiting the generation of the prothrombin activator complex. It is prevalent in 5–10% of SLE cases and, in contradistinction to the name...

... to in the content or advertisements. AIDS AIDS-related complex Autoantibodies Cold agglutinins Acta haemat. 75: 171-173(1986) © 1986 S. Karger AG, Basel 0001-5792/86/0753-0171 $2.75/0 Persistent Cold Agglutinins in AIDS and Related Disorders1 W. Pruzanski, D. Roelcke, E. Donnelly, L.-C. Lui Immunology...

... in the patient’s serum. Anti-i cold agglutinins were not active at 37 °C, whereas antibodies against TPI caused increased 51 Cr release from marked patient’s erythrocytes in vitro. Plasmapheresis removed the autoantibodies effectively and stopped the hemolysis. After 8 weeks, the patient gradually recovered...

...Vandana Pradhan; Suresh Badakere; Kanjaksha Ghosh This study was designed to find out the incidence of various autoantibodies in patients receiving iron chelators. Two groups were studied for comparison. One group consisted of thalassemia major cases on deferiprone (L1) and the second group were...