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Keywords: Acute promyelocytic leukemiaClose
Carlos Andrés Regino, José Domingo Torres, Camilo Cáceres Galvis, Huxlhey Braulio Cabrera, Miguel Ángel Sanz
Acta Haematol (2023) 146 (3): 240–244.
Published Online: 05 June 2023
... of glomerulonephritis and acute myeloid leukemia have been reported in the literature. We describe the first case of a genetically diagnosed acute promyelocytic leukemia presenting with nephrotic range proteinuria that resolved with induction therapy with ATRA and ATO and performed a comprehensive review...
Calogero Lauricella, Rosa Greco, Valentina Mancini, Valentina Motta, Anna Ciraolo, Gabriella De Canal, Elena De Paoli, Giulia Paglino, Valentina Guido, Emanuela Bonoldi, Silvio Veronese, Silvia Soriani
Acta Haematol (2023) 146 (1): 61–67.
Published Online: 14 March 2023
...Calogero Lauricella; Rosa Greco; Valentina Mancini; Valentina Motta; Anna Ciraolo; Gabriella De Canal; Elena De Paoli; Giulia Paglino; Valentina Guido; Emanuela Bonoldi; Silvio Veronese; Silvia Soriani More than 95% of patients with acute promyelocytic leukemia (APL) are characterized...
Muhamed Baljevic, Bogdan Dumitriu, Ju-Whei Lee, Elisabeth M. Paietta, Peter H. Wiernik, Janis Racevskis, Christina Chen, Eytan M. Stein, Robert E. Gallagher, Jacob M. Rowe, Frederick R. Appelbaum, Bayard L. Powell, Richard A. Larson, Steven E. Coutré, Jeffrey Lancet, Mark R. Litzow, Selina M. Luger, Neal S. Young, Martin S. Tallman
Acta Haematol (2016) 136 (4): 210–218.
Published Online: 15 November 2016
... transcriptase catalytic subunit (TERT) and an RNA template (TERC) . Very short telomeres and loss-of-function mutations in the TERT and TERC genes have been reported in acute myeloid leukemia, but the role of telomeres in acute promyelocytic leukemia (APL) has not been well established. We report the results...
Acta Haematol (2015) 134 (2): 101–108.
Published Online: 22 April 2015
...Hongbing Ma; Jing Yang Background: This study aimed to compare the curative effects of the combination therapy of all- trans -retinoic acid (ATRA) and arsenic trioxide (ATO, As 2 O 3 ) with ATRA monotherapy on newly diagnosed acute promyelocytic leukemia (APL). Methods: The studies were retrieved...
Acta Haematol (2014) 132 (3-4): 307–312.
Published Online: 10 September 2014
...Eytan M. Stein; Martin S. Tallman Acute promyelocytic leukemia (APL) is a rare subtype of AML characterized by a reciprocal balanced translocation between chromosomes 15 and 17 that fuses the PML gene with the RARα gene and leads to the leukemic phenotype. Although best described in large clinical...
Dongguang Yang, Fenglin Cao, Xiangmei Ye, Hui Zhao, Xiuhua Liu, Yang Li, Ce Shi, Hongling Wang, Jin Zhou
Acta Haematol (2013) 130 (4): 260–267.
Published Online: 17 July 2013
... receptor is mutated. Implications that Gli proteins are molecular targets of arsenic trioxide (ATO) action prompted us to investigate the expression of Hh signaling in acute promyelocytic leukemia (APL) and the influence of ATO on the Hh signaling pathway in APL. Methods: Quantitative real-time reverse...
Acta Haematol (2013) 130 (4): 223–229.
Published Online: 26 June 2013
...Xing-li Zou; Ke Zeng; Li-ping Xie; Lin Wang; Min Chen; Ting Liu; Ting Niu Extramedullary relapse is a rare phenomenon in patients with acute promyelocytic leukemia (APL), especially that derived from urogenital systems like the testicles. In this report, we describe an APL patient who had received...
Hung Chang, Ming-Chung Kuo, Lee-Yung Shih, Jin-Hou Wu, Tung-Liang Lin, Po Dunn, Tzung-Chih Tang, Yu-Shin Hung, Po-Nan Wang
Acta Haematol (2013) 130 (1): 1–6.
Published Online: 07 March 2013
...Hung Chang; Ming-Chung Kuo; Lee-Yung Shih; Jin-Hou Wu; Tung-Liang Lin; Po Dunn; Tzung-Chih Tang; Yu-Shin Hung; Po-Nan Wang Patients with acute promyelocytic leukemia (APL) are prone to both bleeding and thrombosis. The bleeding complications are well known. In contrast, APL-associated thrombosis...
Acta Haematol (2013) 129 (4): 225–228.
Published Online: 05 January 2013
...Mingjuan Liu; Ji Liu; Lihui Liu; Li Yu; Bing Shi; Liping Ye; Yongqing Zhang; Hu Chen Acute myeloid leukemia (AML) is a rare complication observed after liver transplantation and only a handful of cases have been reported until now. We report a case of acute promyelocytic leukemia (APL) after liver...
Zhitu Zhu, Enze Li, Yangyang Liu, Yu Gao, Hongzhi Sun, Ying Wang, Zhenghua Wang, Xiaomei Liu, Qingjun Wang, Yunpeng Liu
Acta Haematol (2012) 128 (3): 144–150.
Published Online: 10 August 2012
... and apoptosis under certain experimental conditions. However, the detailed mechanism by which bufalin induces the apoptosis of acute promyelocytic leukemia cells is largely unexplored. Methods: The acute promyelocytic leukemia cell line NB4 was treated with bufalin, then the proliferation was evaluated by cell...
Acta Haematol (2011) 126 (3): 152–156.
Published Online: 14 July 2011
...Ofir Wolach; Moshe Yeshurun; Ninette Amariglio; Ofer Shpilberg; Pia Raanani Acute promyelocytic leukemia (APL) may appear rarely as a late complication of the treatment of other primary cancers. Therapy-related APL (tAPL) differs from de novo APL in epidemiological and clinical parameters...
Donatella Ruggero, Michele Baccarani, Anna Guarini, Luigi Gugliotta, Marco Gobbi, Paolo Ricci, Alfonso Zaccaria, Francesco Lauria, Ivana Tomasini, Mauro Fiacchini, Maria Alessandra Santucci, Sante Tura
Acta Haematol (1977) 58 (2): 108–119.
Published Online: 03 March 2009
...Donatella Ruggero; Michele Baccarani; Anna Guarini; Luigi Gugliotta; Marco Gobbi; Paolo Ricci; Alfonso Zaccaria; Francesco Lauria; Ivana Tomasini; Mauro Fiacchini; Maria Alessandra Santucci; Sante Tura Acute promyelocytic leukemia (APL) was diagnosed in 13 of 84 adult patients (15.4%) with acute...
Acta Haematol (1981) 66 (1): 44–49.
Published Online: 26 February 2009
...A. Cantù Rajnoldi; M. Ferrari; G. Cambiaghi; G.C. Secchi; C. Uderzo; G. Masera A variant form of acute promyelocytic leukemia has been recently described, characterized by a particular morphological picture associated with severe disseminated intravascular coagulation, with hyperleukocytosis...
Shuichi Katagiri, Tadahiro Tsubakio, Gakusho Minami, Yoshifumi Higashimoto, Takeshi Yonezawa, Seiichiro Tarui, Shinichi Hori, Noriyuki Suehara, Nobuhiro Taniguchi, Teruo Kitani
Acta Haematol (1983) 70 (2): 119–121.
Published Online: 25 February 2009
... to in the content or advertisements. Acute promyelocytic leukemia Embolization Hemorrhage Case Reports Acta haemat. 70: 119-121(1983) © 1983 S. K argerA G . Basel oooi-5792/83/0702-0119$ 2.75/0 Successful Embolization for Uterine Hemorrhage in a Patient with Acute Promyelocytic Leukemia Shuichi...
Acta Haematol (1989) 81 (1): 15–18.
Published Online: 24 February 2009
...Kenji Okajima; Shin Koga; Hiroaki Okabe; Masayasu lnoue; Kiyoshi Takatsuki Plasma samples from patients with disseminated intravascular coagulation (DIC) associated with acute promyelocytic leukemia (APL) exhibited higher levels of the D-fragment of fibrin and fibrinogen degradation products [FDP(D...
Acta Haematol (1989) 81 (1): 5–9.
Published Online: 24 February 2009
...Amar Das Gupta; Rupa S. Sapre; Ajit S. Shah; Suresh H. Advani; Chandrika N. Nair The leukemic promyelocytes in 37 cases of acute promyelocytic leukemia (APML; FAB, M 3 ) were examined for their cytochemical property. Thirty-two cases (86%) showed strong myeloperoxidase (MPO), chloroacetate esterase...
Eric.J Feldman, Zalmen.A Arlin, Tauseef Ahmed, Abraham Mittelman, Joao.L Ascensao, Carmelo.A Puccio, Nancy Coombe, Paul Baskind
Acta Haematol (1989) 82 (3): 117–121.
Published Online: 20 February 2009
...Eric.J Feldman; Zalmen.A Arlin; Tauseef Ahmed; Abraham Mittelman; Joao.L Ascensao; Carmelo.A Puccio; Nancy Coombe; Paul Baskind Forty-six induction courses were administered to 32 patients with acute promyelocytic leukemia. There were 28 males and 18 females with a median age of 39.5 (range 19–68...
Acta Haematol (1993) 89 (Suppl. 1): 22–27.
Published Online: 18 February 2009
...P. Fenaux All- trans -retinoic acid (ATRA) has demonstrated in vivo and in vitro that it could differentiate leukemic cells in acute promyelocytic leukemia (APL). ATRA yields complete remission (CR) rates of approximately 90% in newly diagnosed and first relapsing APL, in APL resistant to one...
Acta Haematol (1994) 92 (2): 109–112.
Published Online: 18 February 2009
...Yoshinori Shimamoto; Kenji Suga; Masaya Yamaguchi; Kazutaka Kuriyama; Masao Tomonaga A 61-year-old man with acute promyelocytic leukemia (APL) is described in whom some leukemic promyelocytes contained granules similar to those of basophils, and hyperhistaminemia developed after treatment with all...
Acta Haematol (1996) 96 (2): 88–91.
Published Online: 17 February 2009
...Soad Al-Bahar; Ramesh Pandita; A.V. Hoffbran The complication of ‘retinoic acid syndrome’ occurs in 25-30% of patients with acute promyelocytic leukemia (APL) treated with all- trans retinoic acid (ATRA). Early dexamethasone therapy has reduced mortality from this complication. No long-term sequel...