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1-20 of 53
Keywords: Acute lymphoblastic leukemia
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Journal Articles
Uriel Oanunu, Noa Gross Even-Zohar, Shlomzion Aumann, Vladimir Vainstein, Alexander Gural, Moshe E. Gatt, Arnon Haran, Boaz Nachmias
Journal:
Acta Haematologica
Acta Haematol (2025)
Published Online: 30 January 2025
...Uriel Oanunu; Noa Gross Even-Zohar; Shlomzion Aumann; Vladimir Vainstein; Alexander Gural; Moshe E. Gatt; Arnon Haran; Boaz Nachmias Introduction: The treatment protocols of adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) have evolved, with the advent of pediatric...
Journal Articles
Long Non-Coding RNA RP11-252C15.1 Is a Potential Biomarker of Prognosis and Hallmark for Leukemogenesis in Children with B-Cell Precursor Acute Lymphoblastic Leukemia
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2024) 147 (6): 646–660.
Published Online: 25 March 2024
...Lili Pan; Yongzhi Zheng; Hao Zheng Introduction: Improved understanding of the prognostic biomarkers associated with childhood acute lymphoblastic leukemia (ALL) is needed for accurate risk group stratification. This study aimed to identify potential long non-coding RNA (lncRNA) markers...
Journal Articles
Lenalidomide Treatment of Isolated Central Nervous System Relapse in Acute Lymphoblastic Leukemia after Hematopoietic Stem Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapy
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Journal:
Acta Haematologica
Acta Haematol (2024) 147 (5): 592–597.
Published Online: 15 February 2024
...Qing Zhang; Yi Dong; Zhimin Zhai; Lili Tao; Qianshan Tao Introduction: Hematopoietic stem cell transplantation (HSCT) and chimeric antigen receptor T (CAR-T) cell are effective treatments for acute lymphoblastic leukemia (ALL). Various forms of intra- and extramedullary relapses have been reported...
Journal Articles
Outcome and Prognostic Factors of Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Relapsed or Refractory ETV6/RUNX1 -Positive Acute Lymphoblastic Leukemia
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Journal:
Acta Haematologica
Acta Haematol (2024) 147 (5): 534–542.
Published Online: 20 January 2024
.... 2024 ETV6/RUNX1 Allogeneic hematopoietic stem cell transplantation Measurable residual disease Acute lymphoblastic leukemia In pediatric B-acute lymphoblastic leukemia (ALL), the ETV6/RUNX1 rearrangement, t(12;21)(p13;q22), is the most common recurrent genetic abnormality and affects...
Journal Articles
Journal:
Acta Haematologica
Acta Haematol (2024) 147 (4): 391–401.
Published Online: 14 November 2023
...Fausto A. Rios-Olais; Fernando Gil-Lopez; Analy Mora-Cañas; Roberta Demichelis-Gómez Introduction: Tumor lysis syndrome (TLS) occurs frequently during induction therapy for acute lymphoblastic leukemia (ALL). Patients are categorized into intermediate- or high-risk based on the lactate...
Journal Articles
Extracellular Vesicles Derived from Human Bone Marrow Stem Cells Inhibit Acute Lymphoblastic Leukemia Cell Growth by Inhibiting MAPK Pathway via the miR-29b-3p/GDF15 Axis
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Journal:
Acta Haematologica
Acta Haematol (2023) 146 (6): 505–517.
Published Online: 03 November 2022
...Li Zhou; Zhe Shan; Jiangsha Fan Introduction: Acute lymphoblastic leukemia (ALL) is a common hematologic neoplastic disease. This study discussed the effect of extracellular vesicles (EVs) released from bone marrow mesenchymal stem cells (BMSCs) on ALL cells and the mechanism. Methods: BMSCs-EVs...
Journal Articles
Progressive Multifocal Leukoencephalopathy in Relapsed Ph+ Acute Lymphoblastic Leukemia after Cord Blood Transplantation and Blinatumomab Treatment: A Case Report and Literature Review
Available to PurchaseTaro Edahiro, Noriyasu Fukushima, Tatsuya Otani, Masahiro Nakamori, Kazuo Nakamichi, Ren Chishaki, Keita Fujino, Tatsuji Mino, Tetsumi Yoshida, Sayaka Sugihara, Masatoshi Nishizawa, Tatsuo Ichinohe
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (6): 655–661.
Published Online: 27 July 2022
... and refractory acute lymphoblastic leukemia (ALL) than conventional chemotherapy. But, blinatumomab suppresses humoral immunity due to long-lasting B-cell depletion during and after the treatment. The development of PML involves cellular immunity and impairment of humoral immunity. Although few cases...
Journal Articles
Safety and Efficacy of Blinatumomab in Japanese Adult and Pediatric Patients with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Final Results from an Expansion Cohort
Available to PurchaseHiroaki Goto, Chitose Ogawa, Hiroatsu Iida, Keizo Horibe, Iekuni Oh, Satoru Takada, Yoshinobu Maeda, Hironobu Minami, Yasuhiro Nakashima, Joan D. Morris, William Kormany, Yuqi Chen, Toshihiro Miyamoto
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (6): 592–602.
Published Online: 05 July 2022
...) molecule, was evaluated in an expansion cohort of the phase 1b/2 study (NCT02412306) in Japanese adult ( n = 14) and pediatric ( n = 17) patients with relapsed/refractory Philadelphia-negative B-cell precursor (BCP) acute lymphoblastic leukemia (ALL). Materials and methods: Globally recommended...
Journal Articles
Pierre Peterlin, Alice Garnier, Amandine Le Bourgeois, Maxime Jullien, Amélie Seguin, Marion Eveillard, Marie-Christine Béné, Thierry Guillaume, Patrice Chevallier
Journal:
Acta Haematologica
Acta Haematol (2022) 145 (5): 537–541.
Published Online: 20 June 2022
... is very rare and mostly fatal. Treatment recommendations for such a complication are not yet established. Here, we report the dramatic recovery of HLH/MAS following tisagenlecleucel infusion in a young patient with relapsed acute lymphoblastic leukemia using etoposide phosphate (EP). We propose...
Journal Articles
Can Less Intensive Chemotherapy and an Autotransplant Cure Adult T-Cell Acute Lymphoblastic Leukemia?
Available to PurchaseElena Parovichnikova, Vera Troitskaya, Andrey Sokolov, Olga Gavrilina, Zalina Akhmerzaeva, Larissa Kuzmina, Galina Kliasova, Julia Chabaeva, Sergey Kulikov, Sergey Bondarenko, Olga Baranova, Olga Samoilova, Kamil Kaplanov, Natalia Minaeva, Valeriy Savchenko, Russian Acute Lymphoblastic Leukemia Group
Journal:
Acta Haematologica
Acta Haematol (2020) 143 (2): 131–139.
Published Online: 09 October 2019
...Elena Parovichnikova; Vera Troitskaya; Andrey Sokolov; Olga Gavrilina; Zalina Akhmerzaeva; Larissa Kuzmina; Galina Kliasova; Julia Chabaeva; Sergey Kulikov; Sergey Bondarenko; Olga Baranova; Olga Samoilova; Kamil Kaplanov; Natalia Minaeva; Valeriy Savchenko; Russian Acute Lymphoblastic Leukemia...
Journal Articles
Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib
Available to PurchaseFiras El Chaer, Noa G. Holtzman, Edward A. Sausville, Jennie Y. Law, Seung Tae Lee, Vu H. Duong, Maria R. Baer, Rima Koka, Zeba N. Singh, Nancy M. Hardy, Ashkan Emadi
Journal:
Acta Haematologica
Acta Haematol (2019) 141 (2): 107–110.
Published Online: 29 January 2019
...Firas El Chaer; Noa G. Holtzman; Edward A. Sausville; Jennie Y. Law; Seung Tae Lee; Vu H. Duong; Maria R. Baer; Rima Koka; Zeba N. Singh; Nancy M. Hardy; Ashkan Emadi Adults with relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) treated with conventional chemotherapy have...
Journal Articles
A Bortezomib-Based Protocol Induces a High Rate of Complete Remission with Minor Toxicity in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia
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Journal:
Acta Haematologica
Acta Haematol (2018) 140 (4): 209–214.
Published Online: 19 October 2018
...Boaz Nachmias; Adir Shaulov; Moshe E. Gatt; Michael Shapira; Alexander Gural The treatment of relapsed/refractory acute lymphoblastic leukemia (RR-ALL) presents a true clinical challenge. In 2012, a protocol combining bortezomib, dexamethasone, asparaginase, doxorubicin, and vincristine...
Journal Articles
L-Carnitine for Treatment of Pegasparaginase-Induced Hepatotoxicity
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Journal:
Acta Haematologica
Acta Haematol (2016) 135 (4): 208–210.
Published Online: 04 February 2016
...Ruham Alshiekh-Nasany; Dan Douer Introduction: Similar to pediatric regimens, multiple doses of L -asparaginase (PEG-Asp) are being increasingly used in adults with newly diagnosed acute lymphoblastic leukemia (ALL) with promising results. One of the most common side effects of the drug in adults...
Journal Articles
Acute Lymphoblastic Leukemia in Adolescents and Young Adults
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Journal:
Acta Haematologica
Acta Haematol (2014) 132 (3-4): 264–273.
Published Online: 10 September 2014
...Patrick W. Burke; Dan Douer The cure rate of acute lymphoblastic leukemia (ALL) in children is 80%, compared to less than half in adults. A major proportion of this cure rate drop occurs in adolescents and young adults (AYAs). The age range defining this population varies between studies...
Journal Articles
Jae-Sook Ahn, Deok-Hwan Yang, Sung-Hoon Jung, Je-Jung Lee, Inho Kim, Seonyang Park, Joo Seop Chung, Ho-Jin Shin, Dae-Young Kim, Kyoo-Hyung Lee, Joon Ho Moon, Sang Kyun Sohn, Ik-Chan Song, Deog-Yeon Jo, Young Don Joo, Korean Society of Hematology Adult ALL Working Party
Journal:
Acta Haematologica
Acta Haematol (2014) 133 (1): 91–97.
Published Online: 23 August 2014
... is a conventional agent for relapsed or refractory acute lymphoblastic leukemia (ALL). However, an effective combination with other drugs and a feasible dosage has not been identified. A retrospective study of 46 patients with relapsed or refractory ALL was conducted to determine the efficacy of mitoxantrone...
Journal Articles
High Proportions of CD4+ T Cells among Residual Bone Marrow T Cells in Childhood Acute Lymphoblastic Leukemia Are Associated with Favorable Early Responses
Available to PurchaseImke Lustfeld, Bianca Altvater, Martina Ahlmann, Sandra Ligges, Peter Brinkrolf, Annegret Rosemann, Anja Moericke, Claudia Rossig
Journal:
Acta Haematologica
Acta Haematol (2013) 131 (1): 28–36.
Published Online: 19 December 2013
... the phenotypic signature of T cells present at diagnosis in 39 pediatric patients with acute lymphoblastic leukemia (ALL) treated within standardized ALL-BFM study protocols. Previously described age associations of lymphocyte subpopulations in the peripheral blood of healthy children were reproduced in leukemic...
Journal Articles
Precursor B-Cell Lymphoblastic Leukemia with Surface Immunoglobulin Light Chain Expression in 2 Chinese Patients
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Journal:
Acta Haematologica
Acta Haematol (2013) 130 (3): 188–191.
Published Online: 11 June 2013
... for immunophenotyping of this malignancy. Treatment regimens for precursor B-cell ALL are suitable for such cases. Precursor B cell Acute lymphoblastic leukemia Immunophenotype Surface immunoglobulin light chain B-cell acute lymphocytic leukemia (ALL) can be classified into precursor B- and mature B-cell...
Journal Articles
Recent Advancements of Bortezomib in Acute Lymphocytic Leukemia Treatment
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Journal:
Acta Haematologica
Acta Haematol (2013) 129 (4): 207–214.
Published Online: 15 May 2013
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2013 Acute lymphoblastic leukemia Molecular mechanism Bortezomib Acute lymphocytic leukemia (ALL) is a malignant disorder that originates from one single hematopoietic...
Journal Articles
Env Gene Expression of Human Endogenous Retrovirus-K and Human Endogenous Retrovirus-W in Childhood Acute Leukemia Cells
Available to PurchaseDanuta Januszkiewicz-Lewandowska, Karina Nowicka, Jolanta Rembowska, Marta Fichna, Magda Żurawek, Katarzyna Derwich, Jerzy Nowak
Journal:
Acta Haematologica
Acta Haematol (2013) 129 (4): 232–237.
Published Online: 11 January 2013
... could suggest increased expression of HERV-K in leukemic cells. To elucidate the role of endogenous retroviruses in leukemogenesis, studies were undertaken to assess env gene expression of HERV-K and HERV-W in childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Results...
Journal Articles
Acute Megakaryoblastic Leukemia in a Patient with Xeroderma Pigmentosum: Discussion of Pathophysiological, Prognostic, and Toxicological Aspects
Available to PurchaseSnjezana Janjetovic, Ulrike Bacher, Thomas Haalck, Melanie Janning, Carsten Bokemeyer, Walter Fiedler
Journal:
Acta Haematologica
Acta Haematol (2013) 129 (2): 121–125.
Published Online: 28 November 2012
... risk for developing acute lymphoblastic leukemia and acute myeloid leukemia (AML). Case Report: A 33-year-old male XP patient was diagnosed with acute megakaryoblastic leukemia with a complex karyotype. He received standard induction chemotherapy with cytarabine and daunorubicin. After the first cycle...
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