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Keywords: Acute lymphoblastic leukemia
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Subject Area:
Hematology , Oncology
Acta Haematol (2022) 145 (6): 655–661.
Published Online: 27 July 2022
... and refractory acute lymphoblastic leukemia (ALL) than conventional chemotherapy. But, blinatumomab suppresses humoral immunity due to long-lasting B-cell depletion during and after the treatment. The development of PML involves cellular immunity and impairment of humoral immunity. Although few cases...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2022) 145 (6): 592–602.
Published Online: 05 July 2022
...) molecule, was evaluated in an expansion cohort of the phase 1b/2 study (NCT02412306) in Japanese adult ( n = 14) and pediatric ( n = 17) patients with relapsed/refractory Philadelphia-negative B-cell precursor (BCP) acute lymphoblastic leukemia (ALL). Materials and methods: Globally recommended...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2022) 145 (5): 537–541.
Published Online: 20 June 2022
... is very rare and mostly fatal. Treatment recommendations for such a complication are not yet established. Here, we report the dramatic recovery of HLH/MAS following tisagenlecleucel infusion in a young patient with relapsed acute lymphoblastic leukemia using etoposide phosphate (EP). We propose...
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Acta Haematol (2016) 135 (4): 208–210.
Published Online: 04 February 2016
...Ruham Alshiekh-Nasany; Dan Douer Introduction: Similar to pediatric regimens, multiple doses of L -asparaginase (PEG-Asp) are being increasingly used in adults with newly diagnosed acute lymphoblastic leukemia (ALL) with promising results. One of the most common side effects of the drug in adults...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2014) 132 (3-4): 264–273.
Published Online: 10 September 2014
...Patrick W. Burke; Dan Douer The cure rate of acute lymphoblastic leukemia (ALL) in children is 80%, compared to less than half in adults. A major proportion of this cure rate drop occurs in adolescents and young adults (AYAs). The age range defining this population varies between studies...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2014) 133 (1): 91–97.
Published Online: 23 August 2014
... is a conventional agent for relapsed or refractory acute lymphoblastic leukemia (ALL). However, an effective combination with other drugs and a feasible dosage has not been identified. A retrospective study of 46 patients with relapsed or refractory ALL was conducted to determine the efficacy of mitoxantrone...
Journal Articles
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2013) 130 (3): 188–191.
Published Online: 11 June 2013
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Precursor B cell Acute lymphoblastic leukemia Immunophenotype Surface...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2013) 129 (4): 207–214.
Published Online: 15 May 2013
... tolerated and some have promising clinical efficacy that will require subsequent confirmation. Acute lymphoblastic leukemia Molecular mechanism Bortezomib Acute lymphocytic leukemia (ALL) is a malignant disorder that originates from one single hematopoietic precursor committed to the B...
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2013) 129 (4): 232–237.
Published Online: 11 January 2013
... could suggest increased expression of HERV-K in leukemic cells. To elucidate the role of endogenous retroviruses in leukemogenesis, studies were undertaken to assess env gene expression of HERV-K and HERV-W in childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Results...
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