...B.W.B Chan In an autoradiographic investigation, it was found that the inhibition of RNA synthesis in human leukaemic blast cells by actinomycin D (AMD) is dose and time dependent. Chase studies with AMD showed that most of the rapidly labelled RNA is unstable. The decay pattern is biphasic, being...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Actinomycin D Autoradiography Cell culture Cell size and proliferation Leukaemic cells RNA synthesis Acta haemat...

...I. Cserháti; S. Tóth After a single administration of 15 μ g actinomycin D subcutaneously, the platelet count of micefell markedly on the 5th day. At this time trombopoietic activity can be demonstrated in their serum. This is manifested in the increase of the platelet count of recipient animals...