Serum angiotensin-I-converting enzyme (S-ACE) is elevated in active sar-coidosis. In Hodgkin’s disease (HD) there are few reports with different and contrasting results. We studied S-ACE in 23 healthy controls and in 18 untreated and unsplenectomized patients with HD. In the same cases we studied also serum lysozyme. Lysozyme concentration was significantly higher in HD patients compared with normal controls (p < 0.01) and was independent of stage, systemic symptoms and presence of mediastinal involvement. S-ACE activity in HD patients was lower than in healthy controls, but not significantly. The correlation coefficient between the two enzymes showed that there was no significant correlation both in controls and in patients.

Keywords:
Staging, S-ACE, Splenectomy, Hodgkin’s disease, Lysozyme
This content is only available via PDF.
© 1984 S. Karger AG, Basel
1984
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.