Hemoglobin I (α 16 lys →·glu) was identified in association with hemoglobins C and A in a black American woman who had no clinical or hematologic disease. Her erythrocytes contained four major hemoglobins, all of which were separable by DEAE-cellulose column chromatography. Nearly 50% of the total recovered αI-chains were present in combination with βc, suggesting that there may have been preferential formation of the αlβchybrid hemoglobin.
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© 1980 S. Karger AG, Basel
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