In the Arabian peninsula, haemoglobinopathîes, though very interesting, are still far from being fairly established. With the exception of the eastern province of Saudi Arabia, where several aspects of the sickle-cell disease have been focused upon, few reports have appeared in the literature. However, in 1974 one of us (M. A. F. E. H.) has initiated a comprehensive investigation, in collaboration with the Ministry of Health on haemoglobinopathies in various parts of the country. These studies have revealed a new pocket for the sickle-cell gene and a new structural abnormality. In the present report we describe the first finding of Hb·Arab in Saudi Arabia, which may shed more light on the anthropological significance of this haemoglobin variant.

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