Abstract
The first 2 Canadian cases of combinations of Hb D Los Angeles and β-thalas-saemia were found in an Italian family and an East Indian family in Hamilton, Ont. The structure of the Hb D variant was identified by radioimmunoassay. The β+-thalassaemia trait in the Italian family and the β°-thalassaemia trait in the East Indian family were confirmed by studies of globin chain synthesis. Previous cases of Hb D-β-thalassaemia were summarized and family studies of the 2 new cases were presented.
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© 1980 S. Karger AG, Basel
1980
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