The effect of bleeding on spleen colony-forming units (CFU-S) and on in vitro colony-forming cells with colony-stimulating factor (CFU-C) and erythropoietin (CFU-E) has been evaluated. The in vivo and in vitro colony-forming cells of the bone marrow show a decrease which for the CFU-E, CFU-C follows a shortlived increase. In the spleen, all progenitor cells assayed have shown a significant and sustained increase
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© 1977 S. Karger AG, Basel
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