Hb A2 was assayed by means of DE-52 microchromatography in hemolysates from 285 normal subjects and 223 β-thalassemia heterozygotes. No overlap was found between both groups. Comparable results were observed analyzing whole blood samples collected in capillary tubes from 550 normal subjects and 295 β-thalassemia heterozygotes. Our results demonstrate that this technique is useful in a screening program for β-thalassemia trait.
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© 1977 S. Karger AG, Basel
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