The number of circulating platelets gradually increases in splenectomized mice exceeding the starting level of 50% during the second week. Nearly identical amounts of 75Se-methionine given at different times after splenectomy, or in the control group after sham-operation, appear in the circulating platelets of both experimental groups of mice. It is unlikely that increased platelet production could play a decisive role in the development of post-splenectomy thrombocytosis.
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© 1974 S. Karger AG, Basel
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