In fava bean extracts the proteins were separated and characterized by gel filtration on Sephadex G-25 columns, cellogel electrophoresis and analytical ultracentrifugation. The dried extract and its chromatographic fractions were used to detect serum antibodies to fava beans by passive haemagglutination tests. 75 patients affected by acute favism were studied by this method. Haemagglutination tests were positive in 5 patients (6.6%) at the onset of the haemolytic crisis but a rapid fall of the titres was observed in the subsequent days, β1c/β1A and immunoglobulin levels showed no significant changes. Our results do not support the view that hypersensitivity to fava bean may be involved in the haemolysis of acute favism.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.