Neutropenia early in haemodialysis is probably due to the return into the circulation of leucocytes damaged by the first contact with the dialyzing surface. The phenomenon finishes because the damaging action of the membranes may be rapidly eliminated by a protective film of haematic derivation. We did not observe any modifications of the leucocytes on re-using (in the same dialysis) the same dialyzer, provided it is not rinsed. The leucocyte values immediately before the end of dialysis are lower than the starting values. This phenomenon is due to the progressive sedimentation of white cells on the dialyzing membranes during haemodialysis

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