Bone marrow cells from normal and leukaemic individuals were incubated with tritiated diisopropylfluorophosphate (DFP). Stained cells were Diisopropylfluorophosphate classified cytologically and photographed. Following autoradiography the grains overlying the same cells were counted. Myeloblasts took up extremely little DFP. Promyelocytes and, to a slightly lesser extent, myelocytes incorporated DFP very actively. A lower but rather uniform activity was observed in the more mature forms. The grain count varied considerably between individual cells within each maturation compartment
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© 1973 S. Karger AG, Basel
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