Besides the well-known eosinophilic granules, mature eosinophil granulocytes are containing a special form of smaller granules measuring about 100 (20–200) nm. The constant occurrence of these specific microgranules (SM) of eosinophils, as they are named, is proved in eosinophils of 20 different mammalian species out of 7 orders including man. SM are composed of an opaque core bound with an unit membrane. SM may be distinguished into 3 varieties, a spheric (double spheric), a dumbbell, and a cup type. The occurrence of one or the other type depends on the species. SM are supposed to be an essential cytoplasmic detail of mature eosinophils, hitherto widely disregarded

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