Using blood which was anticoagulated with heparin the Heinz body susceptibility against acetyln phenylhydrazine of adult donor erythrocytes increased only slightly in the circulation of newborn infants within 30 h after exchange transfusion. The high susceptibility of the donor erythrocytes found by Kleihauer et al. using ACD for anticoagulation 12 h after exchange transfusion might be due to the effect of Ca++ given during exchange transfusion. During in vitro incubations, the addition of Ca++ increased the Heinz body susceptibility of adult erythrocytes to the level known from newborn infants.
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© 1973 S. Karger AG, Basel
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